Evidence map›Paper›PMID 42775097›Full record

ArticleFrontiers in genetics2026

Genomic analysis identifies candidate supergene architecture for host-feeding behavior in wild

Devojit Kumar Sarma, Sudeesh Warkare, Sweta Mishra, Deepanker Das, Lokendra Rathod, Manoj Kumawat, Siddharth Singh Tomar, Samradhi Singh, Manoj Kumar, Rajnarayan R Tiwari

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Article in Frontiers in genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Devojit Kumar Sarma *ICMR-National Institute for Research in Environmental Health, Bhopal, India.
Sudeesh Warkare *ICMR-National Institute for Research in Environmental Health, Bhopal, India.
Sweta MishraICMR-National Institute for Research in Environmental Health, Bhopal, India.
Deepanker DasICMR-National Institute for Research in Environmental Health, Bhopal, India.
Lokendra RathodICMR-National Institute for Research in Environmental Health, Bhopal, India.
Manoj KumawatIndian Institute of Science Education and Research, Bhopal, India.
Siddharth Singh TomarICMR-National Institute for Research in Environmental Health, Bhopal, India.
Samradhi SinghICMR-National Institute for Research in Environmental Health, Bhopal, India.
Manoj KumarICMR-National Institute for Research in Environmental Health, Bhopal, India.
Rajnarayan R TiwariICMR-National Institute for Research in Environmental Health, Bhopal, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: Here, we present an integrated genome-wide association study (GWAS) and structural variant analysis of host-feeding behavior in 21 field-collected Results: GWAS using a general linear model with five PC covariates (λ = 1.05) identified 11 suggestive SNPs in genes including an actin binding protein on chromosome 2 and G-protein coupled receptor 39 on chromosome 3. Chromosomal inversion analysis using Delly identified an HF-specific inversion on chromosome 2 harboring 13 genes across three functionally coherent chemosensory categories: the sensory developmental regulator tap, odorant receptors Conclusion: The concentration of co-adapted chemosensory genes within a single non-recombining chromosomal unit is consistent with a possible supergene model of anthropophily, paralleling inversion-mediated behavioral divergence in

Indexed as

Aedes aegyptianthropophillychromosomal inversiongenome wide association studies (GWAS)odorant receptorsingle nucleotide polymorphisms (SNP)

Identifiers

PMID42775097
PMCPMC13597056

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