Evidence map›Paper›PMID 42774974›Full record

ArticleBJUI compass2026

Comparing diagnostic prostate cancer biomarkers using a framework of clinically meaningful criteria.

Shu Wang, Behnam Nabavizadeh, Ashwin Ramaswamy, Meena Davuluri, Tenny R Zhang, Michael Tzeng, Nathan Feiertag, Jim C Hu

Abstract read
In one paragraph

Article in BJUI compass, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shu WangDepartment of Urology New York-Presbyterian Hospital/Weill Cornell Medical Center New York New York USA.ORCID https://orcid.org/0000-0001-7347-4707
Behnam NabavizadehDepartment of Urology New York-Presbyterian Hospital/Weill Cornell Medical Center New York New York USA.ORCID https://orcid.org/0000-0003-4378-9243
Ashwin RamaswamyThe Milton and Carroll Petrie Department of Urology Icahn School of Medicine at Mount Sinai New York New York USA.
Meena DavuluriDepartment of Urology New York-Presbyterian Hospital/Weill Cornell Medical Center New York New York USA.
Tenny R ZhangDepartment of Urology New York-Presbyterian Hospital/Weill Cornell Medical Center New York New York USA.
Michael TzengDepartment of Urology New York-Presbyterian Hospital/Weill Cornell Medical Center New York New York USA.
Nathan FeiertagAlbert Einstein College of Medicine Bronx New York USA.
Jim C HuDepartment of Urology New York-Presbyterian Hospital/Weill Cornell Medical Center New York New York USA.ORCID https://orcid.org/0000-0003-2562-8024

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To synthesize existing biomarker literature and generate a framework for meaningful comparison between five commonly used diagnostic prostate cancer biomarkers-prostate health index ( Materials and methods: Ten biomarker characteristics reflecting Results: Nearly all biomarkers possess wide Conclusion: Our framework enables meaningful comparison of diagnostic prostate cancer biomarkers using criteria most salient to patients and clinicians. We demonstrate that the 4KScore currently possesses the best overall features; despite emerging evidence, more clinical utility, comparative and non-White population validation studies are needed.

Indexed as

biomarkersdiagnosisprostate cancer

Identifiers

PMID42774974
PMCPMC13595018

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.