Evidence map›Paper›PMID 42774745›Full record

ArticleCase reports in anesthesiology2026

Remimazolam-Based Anesthesia Without Neuromuscular Blockade for Laparoscopic Surgery in a Patient With Immune-Mediated Necrotizing Myopathy: A Case Report.

Yuka Kobayashi, Ryo Wakabayashi, Kanji Uchida

Abstract read
In one paragraph

Article in Case reports in anesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yuka KobayashiDepartment of Anesthesiology and Pain Relief Center, The University of Tokyo Hospital, 7-3-1 Hongo Bunkyo-ku, Tokyo 113-8655, Japan, u-tokyo.ac.jp.ORCID https://orcid.org/0009-0002-9902-7395
Ryo WakabayashiDepartment of Anesthesiology and Pain Relief Center, The University of Tokyo Hospital, 7-3-1 Hongo Bunkyo-ku, Tokyo 113-8655, Japan, u-tokyo.ac.jp.ORCID https://orcid.org/0000-0002-6198-5806
Kanji UchidaDepartment of Anesthesiology and Pain Relief Center, The University of Tokyo Hospital, 7-3-1 Hongo Bunkyo-ku, Tokyo 113-8655, Japan, u-tokyo.ac.jp.ORCID https://orcid.org/0000-0001-9337-1916

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Immune-mediated necrotizing myopathy causes progressive muscle weakness and may complicate anesthetic management because responses to neuromuscular blocking agents may be unpredictable and residual blockade may further compromise respiratory function. We report a case in which laparoscopic surgery was completed without neuromuscular blocking agents under remimazolam-based total intravenous anesthesia. Case Presentation: A 44-year-old woman with anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase antibody-positive immune-mediated necrotizing myopathy and marked preexisting muscle weakness underwent laparoscopic myomectomy under total intravenous anesthesia with remimazolam and remifentanil without neuromuscular blocking agents. Low-dose rocuronium was immediately available as rescue treatment. Tracheal intubation was completed without coughing or movement. No patient movement occurred during pneumoperitoneum, and surgical exposure remained acceptable. Flumazenil was administered after responsiveness to verbal commands, airway reflexes, and adequate spontaneous ventilation had been confirmed. Tracheal extubation was uneventful, and no postoperative resedation or respiratory compromise occurred. Conclusion: In this patient with immune-mediated necrotizing myopathy and marked preexisting muscle weakness, laparoscopic surgery was completed without neuromuscular blocking agents under remimazolam-based total intravenous anesthesia, with low-dose rocuronium available as rescue treatment. Tracheal intubation was smooth, surgical conditions were acceptable, and postoperative respiratory recovery was uncomplicated.

Indexed as

case reportimmune-mediated necrotizing myopathylaparoscopyneuromuscular blocking agentsremimazolam

Identifiers

PMID42774745
PMCPMC13594569

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.