Evidence map›Paper›PMID 42774740›Full record

ArticleiScience2026

Benchmarking immunoinformatic repertoire assemblies from bulk RNA-seq and PCR-based V(D)J sequencing using PCR-free SMRT RNA sequencing.

Steve Genebrier, Samuel Bastos Serra Trinca, Ophélie Dézé, Marie Cornic, Maiwenn Pineau, Karin Tarte, Michel Cogné

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Steve GenebrierUMR1236, Université de Rennes, INSERM, Etablissement Français du Sang, 35000 Rennes, France.
Samuel Bastos Serra TrincaUMR1236, Université de Rennes, INSERM, Etablissement Français du Sang, 35000 Rennes, France.
Ophélie DézéUMR1236, Université de Rennes, INSERM, Etablissement Français du Sang, 35000 Rennes, France.
Marie CornicSITI Laboratory, Centre Hospitalier Universitaire de Rennes, Etablissement Français du Sang, 35000 Rennes, France.
Maiwenn PineauUMR1236, Université de Rennes, INSERM, Etablissement Français du Sang, 35000 Rennes, France.
Karin TarteUMR1236, Université de Rennes, INSERM, Etablissement Français du Sang, 35000 Rennes, France.
Michel CognéUMR1236, Université de Rennes, INSERM, Etablissement Français du Sang, 35000 Rennes, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune repertoire sequencing (RepSeq) is a crucial immunomonitoring tool, requiring high sensitivity, accuracy, and minimal bias. Although V(D)J mRNA sequencing using 5' rapid amplification of cDNA ends (RACE-RepSeq) is broadly used, its reliance on PCR may create distortions. Alternatively,

Indexed as

benchmarkingdeep sequencingimmune repertoire

Identifiers

PMID42774740
PMCPMC13595170

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.