Evidence map›Paper›PMID 42774657›Full record

ArticleHeart rhythm O22026

Left ventricular wall thickness and functional recovery after atrial fibrillation ablation in patients with systolic dysfunction.

Masato Okada, Nobuaki Tanaka, Yasushi Koyama, Koji Tanaka, Yuko Hirao, Naoko Miyazaki, Kohei Iwasa, Heitaro Watanabe, Yoshitaka Iwanaga, Atsunori Okamura and 3 more

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Article in Heart rhythm O2, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Masato OkadaCardiovascular Center, Sakurabashi Watanabe Advanced Healthcare Hospital, Osaka, Japan.
Nobuaki TanakaCardiovascular Center, Sakurabashi Watanabe Advanced Healthcare Hospital, Osaka, Japan.
Yasushi KoyamaCardiovascular Center, Sakurabashi Watanabe Advanced Healthcare Hospital, Osaka, Japan.
Koji TanakaCardiovascular Center, Sakurabashi Watanabe Advanced Healthcare Hospital, Osaka, Japan.
Yuko HiraoCardiovascular Center, Sakurabashi Watanabe Advanced Healthcare Hospital, Osaka, Japan.
Naoko MiyazakiCardiovascular Center, Sakurabashi Watanabe Advanced Healthcare Hospital, Osaka, Japan.
Kohei IwasaCardiovascular Center, Sakurabashi Watanabe Advanced Healthcare Hospital, Osaka, Japan.
Heitaro WatanabeCardiovascular Center, Sakurabashi Watanabe Advanced Healthcare Hospital, Osaka, Japan.
Yoshitaka IwanagaCardiovascular Center, Sakurabashi Watanabe Advanced Healthcare Hospital, Osaka, Japan.
Atsunori OkamuraCardiovascular Center, Sakurabashi Watanabe Advanced Healthcare Hospital, Osaka, Japan.
Katsuomi IwakuraCardiovascular Center, Sakurabashi Watanabe Advanced Healthcare Hospital, Osaka, Japan.
Koichi InoueCardiovascular Division, National Hospital Organization Osaka National Hospital, Osaka, Japan.
Yasushi SakataDepartment of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Left ventricular functional recovery after atrial fibrillation (AF) ablation varies widely in patients with systolic dysfunction. Objective: This study aimed to evaluate whether baseline left ventricular wall thickness (LVWT) and its regional heterogeneity predict recovery of left ventricular ejection fraction (LVEF) after AF ablation. Methods: Of 5535 consecutive patients undergoing first-time AF ablation (2012-2024), 342 with a baseline LVEF of <50% (median age 64 years; 86% male; 19% with previous myocardial infarction) were retrospectively analyzed. Multidetector computed tomography was performed before ablation, and LVWT was quantified using a 16-segment model at end-diastole. Mean LVWT and its standard deviation (SD) across segments were calculated. The primary endpoint was the 6-month change in LVEF (ΔLVEF) on echocardiography. Results: Median mean LVWT and SD of LVWT were 7.03 mm (6.19-8.00) and 1.20 mm (0.95-1.50), respectively. LVEF improved from 38.7% (32.0%-44.4%) to 56.0% (44.3%-62.0%) at 6 months ( Conclusion: Baseline LVWT and its regional heterogeneity were independently associated with postablation functional recovery in patients with a baseline LVEF of <50%. Preprocedural LVWT assessment may help estimate myocardial reserve and expected functional recovery after AF ablation.

Indexed as

Atrial fibrillationCatheter ablationComputed tomographyHeart failureLeft ventricular wall thickness

Identifiers

PMID42774657
PMCPMC13594468

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.