ReviewInternational journal of reproductive biomedicine2026
The role of date palm pollen in women's health and fertility: A narrative review.
Review in International journal of reproductive biomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 authors.
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Abstract
Infertility is a significant challenge in today's industrialized world, affecting approximately 15% of couples of reproductive age. Around 10% of infertility cases worldwide remain unexplained. As a result, extensive research has focused on exploring natural resources and innovative approaches to preventing and treating infertility. One traditional remedy used since ancient times to enhance sexual potency and fertility in both men and women is date palm pollen (DPP). This study examines the various bioactive compounds in DPP that hold nutritional and therapeutic significance, including phenolic acids, flavonoids, proteins, fatty acids, vitamins, and minerals, which may contribute to fertility. It further analyzes the mechanisms and therapeutic effects of DPP. Evidence from animal and human studies suggests that DPP positively impacts hormonal balance, including estrogen, progesterone, and follicle-stimulating hormone levels, enhances ovarian function, improves egg quality, reduces oxidative stress, alleviates menopausal symptoms such as vaginal dryness and dyspareunia, and boosts women's sexual health. The mechanism of action of DPP appears to involve modulation of the hypothalamic-pituitary-gonadal axis, enhancement of steroidogenesis, and activation of antioxidant defenses. Additionally, it regulates nitric oxide signaling, modulates dopaminergic pathways, suppresses inflammation, and activates key signaling cascades, including PI3K/Akt, MAPK, and Nrf2/ARE. However, challenges remain in this advanced technological era, including variability in composition, pre-purification requirements, and a lack of standardized clinical protocols. Despite these challenges, DPP shows considerable potential for improving fertility. Future studies in the field should prioritize the systematic isolation of bioactive components, detailed mechanistic investigations, rigorous clinical validation, and integration into sustainable bioeconomy strategies.
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