ArticleHeart rhythm O22026
Epidemiologic shift and future projections of atrial fibrillation and flutter in North Africa and the Middle East region: A comprehensive Global Burden of Disease analysis.
Article in Heart rhythm O2, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Owing to the limited availability of data pertaining to atrial fibrillation and flutter (AFF) in the North Africa and the Middle East (NAME) region, a systematic analysis of epidemiologic trends is crucial. Objective: This study aimed to examine the epidemiologic burden of AFF across the NAME using the Global Burden of Disease 2021 and project trends over the next 10 years. Methods: Data on age-standardized incidence (ASIR), prevalence (ASPR), mortality (ASMR), and disability-adjusted life years (ASDRs) were retrieved from the Global Burden of Disease study. Temporal trends between 1990 and 2021 were explored using estimated average percentage change (EAPC) and joinpoint regression. Autoregressive integrated moving average forecasting was applied to project future trends until 2031. Results: Across the NAME region, ASIR (EAPC, 0.03) and ASPR (EAPC, 0.10) demonstrated significant upward trends, exclusively among males. ASMR (EAPC, 0.49) and ASDR (EAPC, 0.23) demonstrated a significant upward trend in both sexes. Joinpoint regression revealed higher ASMR and ASDR burden among females. The burden of disability-adjusted life years was lower for the NAME nation than the global disability-adjusted life year rate across all age groups for both 1990 and 2021. The sociodemographic index was positively correlated with ASIR, ASPR, ASMR, and ASDR. Autoregressive integrated moving average projections indicate a probable rise in ASIR, ASMR, and ASPR, but not in ASDR, by 2031. Conclusion: Our study demonstrated the growing burden of AFF across the NAME region with clear disparities by sex, geography, and economic status. Compared with males, females continue to have a disproportionate share of AFF-related mortality and disability.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.