ArticleJGH open : an open access journal of gastroenterology and hepatology2026
Diagnostic Performance of the Uric Acid-To-Albumin Ratio in Predicting Severity of Acute Pancreatitis.
Article in JGH open : an open access journal of gastroenterology and hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Aim: The uric acid-to-albumin ratio (UAR) has shown prognostic value in several inflammatory conditions, but its role in acute pancreatitis (AP) remains unclear. This study evaluated the prognostic value of UAR for disease severity in patients with AP. Methods: In this single-center, retrospective study, 147 patients hospitalized with acute pancreatitis between February 2025 and June 2026 were included. UAR, systemic immune-inflammation index (SII), and platelet-to-lymphocyte ratio (PLR) were calculated. Disease severity was classified using the revised Atlanta classification and the BISAP score. Diagnostic performance was assessed by receiver operating characteristic (ROC) analysis with pairwise area under the curve (AUC) comparisons (DeLong method). Results: Thirty-eight patients (25.9%) had moderate-to-severe AP. UAR was higher in the moderate-to-severe group than in the mild group (1.65 ± 0.47 vs. 1.27 ± 0.34; Conclusions: UAR is a simple, inexpensive biomarker with potential utility in acute pancreatitis severity assessment. Although not independently predictive, it may provide complementary information alongside clinical and laboratory findings.
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