ArticleFrontiers in pharmacology2026
Structured medication review in elderly patients with chronic kidney disease to assess treatment appropriateness.
Article in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: to determine the proportion of patients aged 75 years or older with chronic kidney disease and an estimated glomerular filtration rate <60 mL/min/1.73 m Methods: A single-centre, uncontrolled longitudinal study evaluating a structured medication review and the subsequent implementation of proposed treatment modifications was conducted in patients aged 75 years or older with an estimated glomerular filtration rate below 60 mL/min/1.73 m Results: Among the 1,937 patients aged ≥75 years registered at the primary care centre, 178 met the study eligibility criteria based on a recorded eGFR <60 mL/min/1.73 m Conclusion: The structured medication review identified a substantial number of potential medication-related problems and proposed treatment modifications in older patients with reduced renal function. Approximately half of the proposed modifications were observed in the electronic prescription at follow-up. However, because the study lacked a control group, the extent to which these changes were attributable to the structured review cannot be determined.
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