Evidence map›Paper›PMID 42774351›Full record

ArticleFood science & nutrition2026

Sulfation Rewrites the Biological Profile of Dietary Flavonoids: Implications for Stability, Redox Signaling, and Inflammation.

Jiří Vrba, Veronika Zapletalová, Jakub Havlásek, Barbora Papoušková, Barbora Petránková, Helena Pelantová, Kateřina Valentová

Abstract read
In one paragraph

Article in Food science & nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiří VrbaDepartment of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry Palacký University Olomouc Czechia.ORCID https://orcid.org/0000-0002-4337-4980
Veronika ZapletalováDepartment of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry Palacký University Olomouc Czechia.
Jakub HavlásekDepartment of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry Palacký University Olomouc Czechia.
Barbora PapouškováDepartment of Analytical Chemistry, Faculty of Science Palacký University Olomouc Czechia.
Barbora PetránkováInstitute of Microbiology of the Czech Academy of Sciences, Laboratory of Biotransformation Prague Czechia.
Helena PelantováInstitute of Microbiology of the Czech Academy of Sciences Laboratory of Molecular Structure Characterization Prague Czechia.
Kateřina ValentováInstitute of Microbiology of the Czech Academy of Sciences, Laboratory of Biotransformation Prague Czechia.ORCID https://orcid.org/0000-0002-7714-5350

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dietary flavonoids undergo extensive Phase II metabolism, yet the functional consequences of sulfation for their biological activity remain poorly understood. In this study, we compared the physicochemical properties and cellular effects of nine structurally diverse flavonoids and their sulfated derivatives. Flavonoid 3'-

Indexed as

flavonoidmetabolismNF‐kappaBNRF2sulfate

Identifiers

PMID42774351
PMCPMC13594397

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.