Evidence map›Paper›PMID 42774095›Full record

ArticleFrontiers in medicine2026

Case Report: Acute angle-closure glaucoma as the initial presentation of autosomal recessive bestrophinopathy caused by compound heterozygous

Ruiqi Lu, Lujia Zhou, Li Tang, Xiumiao Li, Guofan Cao

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ruiqi Lu *The Affiliated Eye Hospital of Nanjing Medical University, Nanjing, China.
Lujia Zhou *The Affiliated Eye Hospital of Nanjing Medical University, Nanjing, China.
Li Tang *The Affiliated Eye Hospital of Nanjing Medical University, Nanjing, China.
Xiumiao LiThe Affiliated Eye Hospital of Nanjing Medical University, Nanjing, China.
Guofan CaoThe Affiliated Eye Hospital of Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Autosomal recessive bestrophinopathy (ARB) arises from compound heterozygous Case presentation: A 29-year-old female presented with refractory angle-closure glaucoma. Clinical examination revealed bilateral elevated intraocular pressure (IOP) and shallow anterior chambers. Retinal imaging demonstrated macular clefting and subretinal fluid. Ocular history was notable for repeated trabeculectomies, which provided transient IOP control. Genetic testing identified compound heterozygous Conclusion: This case represents a rare report of ARB presenting with refractory ACG in a patient harboring compound heterozygous

Indexed as

angle-closure glaucoma (ACG)autosomal recessive bestrophinopathy(ARB)BEST1 genecase reportultrasound cycloplasty (UCP)

Identifiers

PMID42774095
PMCPMC13593448

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.