ArticleFrontiers in cardiovascular medicine2026
Development and validation of a clinical-ready nomogram for predicting postoperative pulmonary infection after coronary artery bypass grafting.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Postoperative pulmonary infection (PPI) remains a significant complication following coronary artery bypass grafting (CABG). This study aimed to identify key risk factors and develop a predictive model to facilitate early risk stratification and individualized intervention strategies. Method: We retrospectively reviewed data from 477 patients who underwent CABG at Zhongnan Hospital of Wuhan University between January, 2020, and December, 2025. Patients were randomly assigned to a training cohort ( Result: Six variables were identified as independent predictors: tracheal intubation >24 h, operative duration >10 h, concomitant surgery, intraoperative red blood cell (RBC) transfusion, intraoperative blood loss, and use of intra-aortic balloon pump (IABP). The model demonstrated good discrimination with an AUC of 0·742 (95% CI 0·668-0·817) in the training cohort and 0·745 (95% CI 0·637-0·853) in the validation cohort. Calibration was excellent in both cohorts (training: Conclusion: The developed nomogram, based on six readily available clinical variables, provides a robust and intuitive tool for identifying patients at high risk of PPI after CABG. Early quantification of risk may assist clinicians in optimizing perioperative management.
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