Evidence map›Paper›PMID 42773477›Full record

ArticleBorderline personality disorder and emotion dysregulation2026

Elevated Negative Affectivity and Psychoticism in individuals with active Nonsuicidal Self-Injury (NSSI) compared with individuals with previous or no NSSI.

Christina Thylander, Magnus Nilsson, Danielle van Westen, Johannes Björkstrand, Sofie Westling

Registry-linked trialAbstract read
In one paragraph

Article in Borderline personality disorder and emotion dysregulation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04905797 (Aspects of Self-harm - Cognition, Imaging and Treatability), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04905797 completednot on this map

Aspects of Self-harm - Cognition, Imaging and Treatability

TypeobservationalSponsorRegion SkaneRan2021 to 2025Enrolled316ConditionsSelf-Harm, Deliberate, Non-Suicidal Self Injury, Attempt Suicide, Personality DisordersArmsEmotional Stop Signal Task, Magnetic Resonance Imaging, World Health Organizations Disability Assessment Schedule (WHODAS 2.0), Personality Inventory for DSM-5 (PID-5), Stop Signal Task (CANTAB)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christina ThylanderPsychiatry, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden. christina.thylander@med.lu.se.ORCID http://orcid.org/0009-0005-7581-0985
Magnus NilssonPsychiatry, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.ORCID http://orcid.org/0000-0002-8394-1345
Danielle van WestenImage and Function, Skane University Hopsital, Lund, Sweden.ORCID http://orcid.org/0000-0001-8649-9874
Johannes BjörkstrandDepartment of Psychology Lund, Lund University, Lund, Sweden.
Sofie WestlingPsychiatry, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.ORCID http://orcid.org/0000-0002-5541-8207

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNon-suicidal self-injury (NSSI) is a transdiagnostic symptom associated with substantial clinical burden and increased risk of suicidal behavior. Although NSSI occurs across a wide range of psychiatric disorders, research has consistently linked it to maladaptive personality traits. However, most studies have compared individuals with NSSI to healthy controls, limiting our understanding of which personality traits are specifically associated with NSSI. The inclusion of clinical control groups may therefore help clarify which personality traits are associated with NSSI rather than with psychopathology more broadly. This study aimed to investigate whether individuals with psychiatric disorders and active NSSI differ in personality traits, as assessed with the Personality Inventory for DSM-5 (PID-5), compared to those with prior but no active NSSI and those without a history of NSSI.

methods231 individuals at a psychiatric outpatient unit completed the PID-5 and the Inventory of Statements About Self-injury and were assessed with regards to demographic information, psychiatric illness and previous suicide attempts. Symptom levels of depression and anxiety were measured. Participants were divided into groups of active NSSI (≥ 5 episodes in the past 12 months; n = 123), previous NSSI (≥ 5 episodes, but none in the past 12 months; n = 68) and no previous history of NSSI (n = 40).

resultsParticipants with active NSSI scored significantly higher in negative affectivity (F(2, 224) = 10.33, p < .001, η

conclusionsActive NSSI seems to be associated with increased traits of negative affectivity and psychoticism. This study contributes with new knowledge regarding NSSI and personality traits, which may guide future research on mechanisms, etiology, and treatment approaches.

trial registrationThe study was registered on Clinical Trials: NCT04905797, registration date April 29, 2021.

Indexed as

Diagnostic and Statistical Manual of Mental DisordersFifth Edition (DSM-5)Nonsuicidal Self-Injury (NSSI)Personality Inventory for DSM-5 (PID-5)

Identifiers

PMID42773477
PMCPMC13599297

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.