Evidence map›Paper›PMID 42773372›Full record

Observational studyInternational ophthalmology2026

Rotational stability and visual outcomes of toric implantable collamer lenses in eyes with horizontal and non-horizontal implanting orientation: an observational study.

Xiaoe Fan, Teruko Fukuyama, Lingling Niu, Xiaohong Zheng, Zhe Zhang, Jing Zhao, Xingtao Zhou

Abstract readObservational Study
In one paragraph

Observational study in International ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Xiaoe Fan *Department of Ophthalmology, Jincheng People's Hospital, Jincheng, 048026, Shanxi, China. fanxiaoe926@163.com.
Teruko Fukuyama *Department of Ophthalmology, Eye & ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Lingling NiuDepartment of Ophthalmology, Eye & ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Xiaohong ZhengDepartment of Ophthalmology, Eye & ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Zhe ZhangDepartment of Ophthalmology, Eye & ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Jing ZhaoDepartment of Ophthalmology, Eye & ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Xingtao ZhouDepartment of Ophthalmology, Eye & ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China. doctzhouxingtao@163.com.

Funding

Jincheng People's Hospital Construction Project JSY-2022D001National Funded Postdoctoral Program of China GZB20230158National Natural Science Foundation of China 82401300
6 · The paper itself

Abstract

purposeTo evaluate the short-term rotational stability and visual outcomes of the toric intraocular collamer lens (TICL) with horizontal and non-horizontal implantation orientation based on the Callisto eye system.

methodsThis observational study analyzed 77 eyes from 51 patients with horizontal (n = 41) and non-horizontal (n = 36) TICL implantation. Examinations were performed preoperatively and at 1 week, 1 month, and 3 months. Outcomes included uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), manifest refraction, and TICL axis position; rotational stability was quantified from dilated slit-lamp photographs. The primary endpoint was mean absolute rotation at 3 months.

resultsAt 3 months, absolute rotation was 3.71 ± 2.72° (horizontal) and 3.15 ± 2.85° (non-horizontal), with no between-group difference (P = 0.385). Rotation ≤ 5° occurred in 73.17% (horizontal) and 88.89% (non-horizontal); ≤ 10° in 100% and 97.22%, respectively. Visual outcomes were excellent and comparable: at 3 months, UDVA 20/20 or better in 100% of eyes in both groups; efficacy index 1.19 ± 0.21 (horizontal) vs 1.17 ± 0.15 (non-horizontal); safety index 1.25 ± 0.21 vs 1.22 ± 0.19. Achieved refraction closely matched target (attempted-vs-achieved slope y = 1.02x + 0.01). Residual cylinder at 3 months was -0.42 ± 0.28 dioptres (D) (horizontal; within ±0.50 D in 87.8%, within ±1.00 D in 97.56%) and -0.33 ± 0.32 D (non-horizontal; within ±0.50 D in 94.44%, within ±1.00 D in 100%); difference non-significant (P = 0.156).

conclusionNon-horizontal EVO-TICL implantation yields rotational stability, safety and efficacy comparable to horizontal placement over 3 months, with small mean rotations and tight refractive predictability. These findings support non-horizontal orientation as a viable alternative when anatomy or vault optimization warrants it.

Indexed as

AstigmatismLens Implantation, IntraocularPhakic Intraocular LensesRefraction, OcularVisual AcuityAdultFemaleFollow-Up StudiesHumansMaleMiddle AgedProsthesis DesignRotationTreatment OutcomeAstigmatismOrientationRotationToric intraocular collamer lens

Identifiers

PMID42773372
PMCPMC13597637

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.