Evidence map›Paper›PMID 42773304›Full record

ArticleTropical animal health and production2026

Bovine appeasing pheromone mitigates long-distance transport stress to improve health and growth performance in beef cattle.

Yue Li, Hai-Peng Wang, Zhong-Qiang Bai, Liang Wang, Xu-Kai Nie, Ting-Ting Xu, Lin Wang

Abstract read
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In one paragraph

Article in Tropical animal health and production, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yue LiCollege of Veterinary Medicine, Shandong Provincial Key Laboratory of Zoonoses, Shandong Agricultural University, Tai'an City, Shandong Province, China.
Hai-Peng WangCollege of Veterinary Medicine, Shandong Provincial Key Laboratory of Zoonoses, Shandong Agricultural University, Tai'an City, Shandong Province, China.
Zhong-Qiang BaiZhongqiang Beef Cattle Breeding Co., Ltd., Yanzhou City, Shandong Province, China.
Liang WangNingbo Sansheng Biological Technology Co., Ltd., Ningbo City, Zhejiang Province, China.
Xu-Kai NieNingbo Sansheng Biological Technology Co., Ltd., Ningbo City, Zhejiang Province, China.
Ting-Ting XuNingbo Sansheng Biological Technology Co., Ltd., Ningbo City, Zhejiang Province, China.
Lin WangCollege of Veterinary Medicine, Shandong Provincial Key Laboratory of Zoonoses, Shandong Agricultural University, Tai'an City, Shandong Province, China. wanglin2013@sdau.edu.cn.ORCID http://orcid.org/0000-0001-6531-1748

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transportation inevitable in modern beef industry disrupts physiological homeostasis and compromises cattle health. This study evaluated bovine appeasing pheromone (BAP) in alleviating transport-induced dysfunctions. Herein, 120 Simmental crossbred bulls (235 ± 5 kg) underwent a 1402-km transport trial with or without BAP treatment (5 mL topically). Data showed BAP decreased (p < 0.01) serum cortisol and haptoglobin levels on day 1 (D1) and D14 post-transport, with cortisol reduced by 32.99% and 47.09%, and haptoglobin by 51.67% and 53.48%, respectively. Concurrently, BAP lowered (p < 0.05) serum IL-1 (by 57.01%) and TNF-α (by 44.12%) on D1, reduced IL-1 (by 22.24%), IL-6 (by 15.18%), and TNF-α (by 23.29%) on D14, and increased (p < 0.01) IgG by 38.58% on D14. Consequently, BAP facilitated metabolic recovery, elevating (p < 0.01) serum glucose and insulin-like growth factor-1 from D14 to D35. Clinically, BAP reduced (p < 0.01) the incidence and duration of respiratory symptoms, increasing (p < 0.05) total feed intake. In summary, BAP protects beef cattle against transport stress-induced health impairment and growth decline by maintaining physiological homeostasis, offering a highly practical intervention to optimize animal welfare in the modern beef industry.

Indexed as

PheromonesStress, PhysiologicalTransportationAnimal HusbandryAnimalsBlood GlucoseCattleHaptoglobinsHydrocortisoneMaleBlood GlucoseHaptoglobinsHydrocortisonePheromonesBovine appeasing pheromoneGrowth performanceNeuroendocrine responsePhysiological homeostasisTransport stress

Identifiers

PMID42773304

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.