ArticleInternational journal of obesity (2005)2026
Adiposity trajectory as a predictor of chronic and multisite pain in the transition from childhood to adolescence: A prospective study of a large birth cohort.
Article in International journal of obesity (2005), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
BACKGROUND/
objectivesThe association between obesity and pain may have relevant population health implications starting in young ages. We aimed to quantify associations between adiposity and pain in the general population, from 4 to 13 years of age, using complementary longitudinal approaches.
methodsParticipants were from Generation XXI, a population-based cohort assembled at birth in Porto, Portugal, and re-evaluated at 4, 7, 10, and 13 years of age (n = 4563). Pain was assessed using the Luebeck Pain Questionnaire and classified as chronic (above three months) or multisite (two or more sites). Adiposity parameters included fat mass percentage and age- and sex-standardized body mass index scores (BMI z-scores). Associations between individual adiposity trajectories from ages 4 to 13, extracted from mixed-effects polynomial trend models, and pain measures at age 13 were tested using logistic regression adjusted for pubertal development and practice of programmed physical activity. Bidirectionality was assessed using cross-lagged analysis.
resultsAmong girls, quadratic fat mass (FM) trajectories, characterized by accelerated fat mass gain, were associated with increased odds of chronic pain (quadratic coefficient odds ratio [
conclusionHigher adiposity during childhood and early adolescence was a predictor of chronic and multisite pain reports at age 13 among girls.
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