Evidence map›Paper›PMID 42773137›Full record

ArticleNature communications2026

A Hadean timeline for the emergence of the RNA World.

Oleg Abramov, Anna Medvegy, Barbara Kremer, Stephen J Mojzsis

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Oleg AbramovBayerisches Geoinstitut (BGI), University of Bayreuth, Universitätsstrasse 30, 95447, Bayreuth, Germany. abramov@psi.edu.ORCID http://orcid.org/0000-0002-2884-2299
Anna MedvegyHUN-REN Research Centre for Astronomy and Earth Sciences (CSFK), MTA Centre of Excellence, Konkoly-Thege Miklós út 15-17, 1121, Budapest, Hungary.
Barbara KremerInstitute of Paleobiology, Polish Academy of Sciences, Twarda 51/55, 00-818, Warsaw, Poland.
Stephen J MojzsisBayerisches Geoinstitut (BGI), University of Bayreuth, Universitätsstrasse 30, 95447, Bayreuth, Germany. stephen.mojzsis@uni-bayreuth.de.ORCID http://orcid.org/0000-0003-0000-125X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Estimates for when life emerged on Earth range from ca. 3.8 Ga (Eoarchean) to the Hadean eon (≥4.0-4.5 Ga). Here, we conclude that a proposed early stage of life - the RNA World - appeared at ca. 4.33 Ga by tracking the near-surface thermal stability of key biomolecules comprising postulated RNA organisms. We apply a global three-dimensional numerical model to analyse the thermal evolution profile of Hadean crust in response to late accretion bombardment. Results show that frequent global sterilization events persisted up until about 4.4 Ga owing to hot ejecta deposition, rock vapour condensation, and enhanced geothermal gradients. Later, conditions became favorable to persistent biochemistry by supporting interconnected zones of biomolecule stability associated with extensive energy-rich hydrothermal oases. We identify an optimal time for the RNA World that dovetails with the emergence of the Last Universal Common Ancestor (LUCA) population.

Indexed as

Origin of LifeRNAEarth, PlanetEvolution, MolecularRNA

Identifiers

PMID42773137
PMCPMC13597498

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.