Evidence map›Paper›PMID 42771803›Full record

ArticleEndocrinology, diabetes & metabolism2026

Higher Post-Operative L-Thyroxine Dosage Needed After Right Compared to Left-Lobe Hemithyroidectomy.

Carola Deischinger, Michael Krebs, Thomas Scherer, Christian Scheuba, Alexandra Kautzky-Willer, Lana Kosi-Trebotic

Abstract readComparative Study
In one paragraph

Article in Endocrinology, diabetes & metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carola DeischingerGender Medicine Unit, Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0003-4857-222X
Michael KrebsGender Medicine Unit, Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0002-9265-7274
Thomas SchererGender Medicine Unit, Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0003-4980-706X
Christian ScheubaDivision of Endocrine Surgery, Department of General Surgery, Medical University of Vienna, Vienna, Austria.
Alexandra Kautzky-WillerGender Medicine Unit, Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0002-3520-4105
Lana Kosi-TreboticGender Medicine Unit, Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeUsually, the right lobe of the thyroid gland is larger than the left lobe. Post hemithyroidectomy, the remaining lobe grows by up to 30% as compensation. Thyroxine replacement is still necessary for 22%-60% of all patients. We aimed at investigating whether a right-lobe hemithyroidectomy requires higher postoperative levothyroxine dosages. PATIENTS AND

methods426 adult patients who received a hemithyroidectomy and a follow-up visit (median 9 months post-surgery) at the Medical University of Vienna between 1994 and 2018 were identified and investigated in this retrospective study with a weight and pre-surgery TSH-adjusted model.

resultsPatients required a higher mean levothyroxine dosage after right-lobe hemithyroidectomy (mean = 68.1 μg/day, p = 0.018) compared to the left lobe (mean = 60.2 μg/day).

conclusionPatients require roughly 13% more levothyroxine substitution after hemithyroidectomy of the right lobe compared to the left lobe, which should be considered in post-op care.

Indexed as

Hormone Replacement TherapyPostoperative CareThyroidectomyThyroxineAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedRetrospective StudiesThyroid GlandThyroxinehemithyroidectomylevothyroxinelobectomypostoperative levothyroxine dosagethyroid

Identifiers

PMID42771803
PMCPMC13597070

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.