Evidence map›Paper›PMID 42771668›Full record

ArticlePLOS global public health2026

HIV self-testing preferences among adolescent girls and young women (AGYW) in urban settings in Uganda: A discrete choice experiment.

Laban Muteebwa, Patience A Muwanguzi, Shivan Nuwasiima, Ivan Ahimbisibwe, Edson Atwine, Dan Muramuzi, Cathbert Tumusiime, Fred C Semitala, Joanita Nangendo

Abstract read
In one paragraph

Article in PLOS global public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Laban MuteebwaDepartment of Medicine, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.ORCID https://orcid.org/0000-0002-5807-5799
Patience A MuwanguziDepartment of Nursing, School of Health Sciences, College of Health Sciences, Makerere University, Kampala, Uganda.
Shivan NuwasiimaClinical Epidemiology Unit, School of Medicine, College of health Sciences, Makerere University, Kampala, Uganda.
Ivan AhimbisibweClinical Epidemiology Unit, School of Medicine, College of health Sciences, Makerere University, Kampala, Uganda.ORCID https://orcid.org/0009-0002-8315-4891
Edson AtwineFaculty of Graduate Studies, Makerere University Business School, Makerere University, Kampala, Uganda.
Dan MuramuziDepartment of Pharmacy, School of Health Sciences, College of Health Sciences, Makerere University, Kampala, Uganda.ORCID https://orcid.org/0000-0002-0193-6252
Cathbert TumusiimeDirectorate of Research, Baylor College of Medicine Children's Foundation-Uganda, Kampala, Uganda.ORCID https://orcid.org/0000-0002-5289-673X
Fred C SemitalaDepartment of Medicine, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.ORCID https://orcid.org/0000-0002-0624-7640
Joanita NangendoDepartment of Medicine, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.ORCID https://orcid.org/0000-0002-0458-2111

Funding

Building Implementation Science Capacity at Makerere University to Strengthen the Response to the HIV/AIDS Epidemic in UgandaD43TW010037 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI KAMYA, MOSES ROBERT, SEMITALA, FRED C · 2015 to 2025
$3.3M
FIC NIH HHS D43 TW010037
6 · The paper itself

Abstract

HIV self-testing (HIVST) is a crucial innovation for improving testing coverage, particularly among adolescent girls and young women (AGYW) who are inadequately reached by standard provider-assisted HIV testing approaches. Understanding their preferences for HIVST services is essential for designing models that optimize uptake. We assessed the HIVST preferences among AGYW at a higher risk of acquiring HIV living in urban Uganda. We enrolled AGYW at a higher risk of HIV using a community-based convenience sampling in a discrete choice experiment (DCE). Each participant completed eight choice sets, each comprising of two hypothetical HIVST service alternatives and an opt-out option. The four attributes included level of assistance (assisted versus unassisted), distribution model (facility-based versus community-based), delivery channel (primary versus secondary) and sample type (oral swab versus blood). A mixed logit model was used to estimate the marginal utilities, relative importance (RI), HIVST profile utilities and predicted uptake (compared to opt-out). Between December 2024 and May 2025, 340 participants were enrolled with mean age 19.8 years (standard deviation (SD): 2.6), and 65.9% of them were not in school. In the main effects model, participants preferred; facility-based over community-based distribution model (β = 0.14 (95% confidence interval (CI): 0.06, 0.23)), primary over secondary delivery channel (β = 0.09 (95% CI: 0.00, 0.17)), and unassisted over assisted testing (β = 0.46 (95% CI: 0.37, 0.54). The sample type didn't significantly influence the preferences of participants to use HIVST (β = 0.05 (95%CI: -0.04, 0.13). The level of assistance emerged as the most important attribute (RI: 60%), followed by facility-based distribution model (RI: 18.9%) and primary delivery channel (RI: 12.2%). There was a significant interaction between delivery channel and level of assistance (β = 0.66 (95% CI: 0.07, 1.24)). Primary delivery was preferred over secondary delivery when testing was unassisted (β = 0.41 (95% CI: 0.11, 0.71), but not when testing was assisted (β = -0.25 (95% CI: -0.56, 0.06). AGYW preferred HIVST models combining primary delivery with unassisted testing while facility-based distribution also increased preference. This highlights the importance of considering both individual attributes and their interaction when designing HIV delivery models.

Identifiers

PMID42771668
PMCPMC13596813

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.