Evidence map›Paper›PMID 42771493›Full record

Observational studyRevista medica del Instituto Mexicano del Seguro Social2026

[Work reintegration in patients treated for diabetic macular edema].

Sarah Melissa Peña-Durán, Gloria Paulina Trujillo-Sánchez, Luis Miguel López-Montero

Abstract readObservational StudyEnglish Abstract
In one paragraph

Observational study in Revista medica del Instituto Mexicano del Seguro Social, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sarah Melissa Peña-DuránInstituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Especialidades No. 1, Servicio de Oftalmología. León, Guanajuato, México.ORCID 0009-0003-0458-5202
Gloria Paulina Trujillo-SánchezInstituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Especialidades No. 1, Servicio de Oftalmología. León, Guanajuato, México.ORCID 0000-0002-1810-9587
Luis Miguel López-MonteroCentro de Investigaciones en Óptica, Laboratorio de Óptica de la Visión. León, Guanajuato, México.ORCID 0000-0003-2826-6022

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Type 2 diabetes mellitus (T2DM) has increased in prevalence, and with it, complications such as diabetic retinopathy and diabetic macular edema (DME), which cause disability due to visual impairment and high medical and social costs, as it is the leading cause of blindness in the economically active population aged 18 to 64. Intravitreal anti-angiogenic (anti-VEGF) therapy is the first line of treatment. Objective: To estimate the proportion of patients with DME who return to work and the time required after treatment. Material and methods: Based on literature and local data with a response rate ≥ 60%, an observational study was planned; the analysis was descriptive, and the post-intervention comparison was performed using the chi-square test. Results: 45 patients were included (26 women, 19 men; 57.4 ± 5.0 years; T2DM duration 16 [12-20] years), with diabetic retinopathy and macular edema: proliferative 53.3%, mild non-proliferative 22.2%, severe 17.8%, moderate 6.7%. Functional success (visual acuity, [VA] ≥ 0.5) was achieved in 70% of mild non-proliferative cases and 25% of proliferative/severe cases. Mean gain in decimal VA was + 0.127 RE and + 0.090 LE. A total of 33.3% reached VA ≥ 0.5 after loading doses, a functional level compatible with reading and precision tasks. An inverse correlation was observed between central macular thickness and final VA. Conclusions: Early intervention maximized the benefit with intravitreal anti-VEGF, improving function and anatomy in DME. A significant proportion of patients of working age returned to work, reducing days of disability and improving quality of life.

Indexed as

Angiogenesis InhibitorsDiabetic RetinopathyMacular EdemaDiabetes Mellitus, Type 2FemaleHumansIntravitreal InjectionsMaleMiddle AgedTime FactorsAngiogenesis InhibitorsDiabetic RetinopathyDrug, Anti-AngiogenicEdema MacularFármaco AntiangiogénicoMacular EdemaRetinopatía Diabética

Identifiers

PMID42771493
PMCPMC13610904

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.