Evidence map›Paper›PMID 42771076›Full record

ArticleInternational microbiology : the official journal of the Spanish Society for Microbiology2026

Epoxidation of ent-pimara-8(14),15-dien-19-oic acid by whole cells of the endophytic fungus Aspergillus sclerotiorum.

Zia Ud Din, Lívia S de Medeiros, L M Abreu, Danielle Lazarin-Bidóia, Débora Botura Scariot, Francielle Pelegrin Garcia, Jéssica Carreira de Paula, Celso Vataru Nakamura, Taicia P Fill, Edson Rodrigues-Filho

Abstract read
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In one paragraph

Article in International microbiology : the official journal of the Spanish Society for Microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zia Ud DinLaBioMMi, Departament of Chemistry, Federal University of São Carlos, Rod. Washington Luiz, Km 235, CP 676, 13.565-905, São Carlos, SP, Brazil.
Lívia S de MedeirosDepartamento de Química, Universidade Federal de São Paulo (UNIFESP), Rua São Nicolau, 210, CEP 09913-030, Diadema, SP, Brazil.
L M AbreuDepartamento de Fitopatologia, Universidade Federal de Lavras, PO Box 3037, 37200-000, Lavras, MG, Brazil.
Danielle Lazarin-BidóiaLaboratório de Inovação Tecnológica no Desenvolvimento de Fármacos e Cosméticos, Universidade Estadual de Maringá, Av. Colombo 5790, Bloco B-08, 87020- 900, Maringá, PR, Brazil.
Débora Botura ScariotLaboratório de Inovação Tecnológica no Desenvolvimento de Fármacos e Cosméticos, Universidade Estadual de Maringá, Av. Colombo 5790, Bloco B-08, 87020- 900, Maringá, PR, Brazil.
Francielle Pelegrin GarciaLaboratório de Inovação Tecnológica no Desenvolvimento de Fármacos e Cosméticos, Universidade Estadual de Maringá, Av. Colombo 5790, Bloco B-08, 87020- 900, Maringá, PR, Brazil.
Jéssica Carreira de PaulaLaboratório de Inovação Tecnológica no Desenvolvimento de Fármacos e Cosméticos, Universidade Estadual de Maringá, Av. Colombo 5790, Bloco B-08, 87020- 900, Maringá, PR, Brazil.
Celso Vataru NakamuraLaboratório de Inovação Tecnológica no Desenvolvimento de Fármacos e Cosméticos, Universidade Estadual de Maringá, Av. Colombo 5790, Bloco B-08, 87020- 900, Maringá, PR, Brazil.
Taicia P FillInstitute of Chemistry, Universidade Estadual de Campinas, CP 6154, 13083-970, Campinas, SP, Brazil.
Edson Rodrigues-FilhoLaBioMMi, Departament of Chemistry, Federal University of São Carlos, Rod. Washington Luiz, Km 235, CP 676, 13.565-905, São Carlos, SP, Brazil. edson.rf@ufscar.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diterpene ent-pimara-8(14),15-dien-19-oic acid (1) was converted into four oxidized diterpenes, 15,16-epoxy-ent-pimar-8(14)-en-19-oic acid (1a), 15,16-epoxy-17-hydrxy-ent-pimar-8(14)-en-19-oic acid (1b), 15,16-dihydroxy-ent-pimar-8(14)-en-19-oic acid (1c), and 15-oxo-16-hydroxy-ent-pimar-8(14)-en-19-oic acid (1d), when added to Aspergillus sclerotiorum cells growing in liquid cultures, being 1b and 1d non described substances. A. sclerotiorum oxidized the double-bound Δ

Indexed as

Aspergillus sclerotiorumBiotransformationCupressus lusitanicaDiterpeneEndophyticent-pimar-8(14),15-dien-19-oic acid

Identifiers

PMID42771076

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.