Evidence map›Paper›PMID 42771046›Full record

ArticleWorld journal of urology2026

Dorsal inlay lingual mucosa graft urethroplasty with artificial dermis donor repair for female urethral stricture.

Hang Guo, Yangwang Jin, Chao Deng, Kaile Zhang, Tao Liang, Lujie Song, Yuemin Xu, Yinglong Sa, Qiang Fu

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Article in World journal of urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hang Guo *Department of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Eastern Institute of Urologic Reconstruction, Shanghai Jiao Tong University, Shanghai, 200233, China.
Yangwang Jin *Department of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Eastern Institute of Urologic Reconstruction, Shanghai Jiao Tong University, Shanghai, 200233, China.
Chao DengDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Eastern Institute of Urologic Reconstruction, Shanghai Jiao Tong University, Shanghai, 200233, China.
Kaile ZhangDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Eastern Institute of Urologic Reconstruction, Shanghai Jiao Tong University, Shanghai, 200233, China.
Tao LiangDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Eastern Institute of Urologic Reconstruction, Shanghai Jiao Tong University, Shanghai, 200233, China.
Lujie SongDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Eastern Institute of Urologic Reconstruction, Shanghai Jiao Tong University, Shanghai, 200233, China.
Yuemin XuDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Eastern Institute of Urologic Reconstruction, Shanghai Jiao Tong University, Shanghai, 200233, China.
Yinglong SaDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Eastern Institute of Urologic Reconstruction, Shanghai Jiao Tong University, Shanghai, 200233, China.
Qiang FuDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Eastern Institute of Urologic Reconstruction, Shanghai Jiao Tong University, Shanghai, 200233, China. jamesqfu@126.com.

Funding

2022 Shanghai Leading Talent Training Program 026National Natural Science Foundation of China 82370684 and 82170694Shanghai 'Science and Technology Innovation Action Plan' Medical Innovation Research Project 22Y11905000
6 · The paper itself

Abstract

objectiveFemale urethral stricture (FUS) is a rare but challenging condition with no consensus on optimal management. Although the lingual mucosa graft (LMG) is an effective substitute tissue, concerns regarding donor site morbidity limit its use. This study evaluated the outcomes of dorsal inlay LMG urethroplasty for FUS and the effect of bilayer artificial dermis reconstruction on lingual donor site recovery.

methodsWe retrospectively reviewed 20 women who underwent dorsal inlay LMG urethroplasty between December 2019 and June 2024. The lingual donor defect was reconstructed using bilayer artificial dermis rather than primary closure. Outcomes included maximum urinary flow rate (Qmax), AUA Symptom Index (AUA-SI), and Quality of Life (QoL). Surgical success was defined as postoperative Qmax > 12 mL/s without additional intervention. Continence was assessed using the ICIQ-UI-SF. Donor site morbidity (pain, speech, diet) was evaluated using the Oral Mucositis Daily Questionnaire.

resultsMedian age was 52 years, median stricture length 2 cm, and median follow-up 16 months. Surgical success was achieved in 95% (19/20) of patients. At 12 months, voiding parameters improved significantly (p < 0.001): median Qmax increased from 6.5 to 20.5 mL/s, AUA-SI decreased from 25 to 4, and QoL improved from 5 to 1. No de novo stress or urge incontinence occurred. Donor site recovery was rapid, with pain resolving by day 14 and all patients regaining normal speech and diet without tongue deviation, contracture, or permanent numbness.

conclusionsDorsal inlay LMG urethroplasty is safe and effective for FUS in this cohort. Bilayer artificial dermis reconstruction of the donor site appears to facilitate rapid functional recovery and may mitigate concerns regarding lingual mucosa harvesting, though further comparative studies are required to confirm these benefits.

Indexed as

Mouth MucosaPlastic Surgery ProceduresSkin, ArtificialUrethraUrethral StrictureAdultAgedFemaleHumansMiddle AgedRetrospective StudiesTreatment OutcomeArtificial dermisDorsal inlayFemale urethral strictureLingual mucosa graftUrethroplasty

Identifiers

PMID42771046

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.