Observational studyActa orthopaedica2026
Development of osteoarthritis in adults with untreated hip dysplasia: a longitudinal observational study.
Observational study in Acta orthopaedica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
5 authors.
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Abstract
background and purposeAlthough hip dysplasia is a risk factor for osteoarthritis (OA), its natural progression in adults remains poorly understood. In a longitudinal observational study, we aimed to estimate differences in OA incidence, time to OA, and minimum joint space width (JSW) between dysplastic hips and contralateral non-dysplastic hips.
methodsAdults aged 20-70 years who underwent pelvic radiographs in Malmö, Sweden, during 2007-2008 were included. Inclusion criteria were unilateral hip dysplasia (lateral center edge angle ≤ 20°), no OA at baseline, and available follow-up imaging of both hips. OA incidence was assessed using last available follow-up imaging, whereas minimum JSW was measured bilaterally on the last available radiograph of native hips.
results50 participants (median age 47 years, IQR 39-62, 36 women) were included, with median follow-up 12.5 years (IQR 7.8-14.7). OA developed in 19/50 dysplastic hips and 16/50 non-dysplastic hips, corresponding to a paired risk difference of 6 percentage points (95% confidence interval [CI] -7 to 20). Mean time to OA was 8.2 years (SD 5.2) for dysplastic hips and 9.6 years (SD 5.1) for non-dysplastic hips (mean difference -1.2 years, CI -4.8 to 2.4). Minimum JSW at follow-up was 3.3 mm (SD 1.3) in dysplastic hips and 3.5 mm (SD 0.9) in non-dysplastic hips (mean difference -0.2 mm, CI - 0.6 to 0.2).
conclusionNo clear differences were observed in OA incidence, time to OA, or minimum JSW between dysplastic and contralateral non-dysplastic hips.
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