ArticleNeurosurgery practice2026
The Impacts of Marijuana Usage on Nerve Transfer Outcomes: A Retrospective Cohort Study.
Article in Neurosurgery practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND AND
objectivesMarijuana is often used by patients with peripheral nerve injuries for pain management, but its impact on nerve transfer surgery outcomes remains unexplored.
methodsThis retrospective cohort study reviewed the records of patients age 18 years and older who underwent radial-to-axillary or ulnar fascicle to biceps fascicle (Oberlin) nerve transfers at a single institution from 2014 to 2023. Data collected included demographics, surgical details, injury characteristics, marijuana use, and Medical Research Council strength scores from preoperative evaluations to 24 months after operation. Statistical analyses were performed using χ
resultsForty-nine patients' (67 surgeries, 42 males, mean age 43.3 ± 17.3 years) records were analyzed. Radial-to-axillary nerve transfer and Oberlin transfer were performed in 18 patients. Radial-to-axillary nerve transfer was performed in 38 patients, and Oberlin transfer was performed in 29 patients. No significant differences were found regarding marijuana use and achievement of functional strength at 6, 12, 18, or 24 months postoperatively. No significant associations were found controlling for the type of surgery. Patients showing notable improvement between 6- and 24-month intervals and the preoperative and 24-month intervals were significantly younger than those without improvement (
conclusionIn patients undergoing radial-to-axillary nerve transfer or Oberlin nerve transfer surgery, marijuana use did not influence functional strength outcomes. Improvement in functional strength was associated with younger age and shorter time between injury and surgery.
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