Evidence map›Paper›PMID 42770115›Full record

ArticleCureus2026

A Case Report of a Fulminant Necrotizing Fasciitis of the Upper Extremity in an Immunocompromised Patient.

Reagan Boyett, Gregory S Morris, Alexandra G Smith, John B Boyett, Joseph P Boyett

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Reagan BoyettMedicine, Edward Via College of Osteopathic Medicine, Auburn, USA.
Gregory S MorrisMedicine, Edward Via College of Osteopathic Medicine, Auburn, USA.
Alexandra G SmithResearch, Alabama College of Osteopathic Medicine, Dothan, USA.
John B BoyettOrthopedic Surgery, Athens-Limestone Hospital, Athens, USA.
Joseph P BoyettOrthopedic Surgery, Athens-Limestone Hospital, Athens, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Necrotizing fasciitis (NF) is a rare, extremely aggressive, and limb-and-life-threatening soft tissue infection requiring emergent surgical intervention. Diagnosis is often delayed by nonspecific early findings, and immunocompromised patients are at particular risk for fulminant, atypical presentations. We present a case of a 70-year-old male with a remote history of multiple myeloma treated with stem cell transplant who developed extensive NF of the right upper extremity within 24 hours of minor blunt trauma. Despite emergent surgical debridement, the patient progressed to septic shock and ultimately required above-elbow amputation. He was recovering well at the four-month follow-up visit. This case highlights the diagnostic challenge posed by NF following trivial trauma in patients with occult or remote immunosuppression and underscores the importance of a low threshold for surgical exploration when clinical suspicion is high despite an unimpressive mechanism of injury.

Indexed as

immunocompromised statusmultidisciplinary managementnecrotizing fasciitis (nf)stem cell transplant recipientupper extremity amputation

Identifiers

PMID42770115
PMCPMC13592732

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.