Evidence map›Paper›PMID 42770110›Full record

ArticleRedox biochemistry and chemistry2026

Ascorbate-catalyzed reductive nitrosylation of ferric myoglobin.

Thilini Karunarathna, Stephen R Baker, Julian Flanagan, Troy A Stich, Jesús Tejero, Matthew R Dent, Elizabeth Rochon, Anthony W DeMartino, Mark T Gladwin, Daniel B Kim-Shapiro

Abstract read
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In one paragraph

Article in Redox biochemistry and chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Thilini KarunarathnaDepartment of Physics, Winston-Salem, NC, 27109, USA.
Stephen R BakerDepartment of Physics, Winston-Salem, NC, 27109, USA.ORCID 0000-0002-3147-4925
Julian FlanaganDepartment of Physics, Winston-Salem, NC, 27109, USA.ORCID 0009-0000-0283-6790
Troy A StichDepartment of Chemistry Wake Forest University, Winston-Salem, NC, 27109, USA.ORCID 0000-0003-0710-1456
Jesús TejeroHeart, Lung, Blood, and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, 15261, USA.ORCID 0000-0003-3245-9978
Matthew R DentDepartment of Chemistry, Wayne State University, Detroit, MI, 48202, USA.ORCID 0000-0002-7704-4867
Elizabeth RochonDepartment of Medicine, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.ORCID 0000-0002-6255-9817
Anthony W DeMartinoDepartment of Medicine, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.ORCID 0000-0001-5303-5758
Mark T GladwinDepartment of Medicine, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.ORCID 0000-0001-7267-9006
Daniel B Kim-ShapiroDepartment of Physics, Winston-Salem, NC, 27109, USA.ORCID 0000-0003-4383-3101

Funding

Storage Lesion in Banked Blood Due to Disruption of Nitric Oxide HomeostasisR01HL098032 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Mark T Gladwin · 2009 to 2026
$12.5M
Antidote for inhaled CO poisoning based on mutationally engineered neuroglobinR01HL125886 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Mark T Gladwin, Jesus Tejero Bravo · 2015 to 2026
$7.9M
Optimization of a carbon monoxide (CO) sensing hemoprotein for applications as an antidote for CO poisoning and a biosensor for CO detection in living cellsR00HL168224 · NHLBI · WAYNE STATE UNIVERSITY · PI Matthew Ryan Dent · 2024 to 2026
$746k
NHLBI NIH HHS R00 HL168224NHLBI NIH HHS R01 HL098032NHLBI NIH HHS R01 HL125886
6 · The paper itself

Abstract

Myoglobin plays a key role in oxygen storage and delivery through oxygen binding and release from the ferrous (Fe

Indexed as

Ascorbic acidGlutathioneLipid peroxidationMyoglobinNitric oxideSpectroscopy

Identifiers

PMID42770110
PMCPMC13592669

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.