Evidence map›Paper›PMID 42770099›Full record

ReviewAvicenna journal of phytomedicine2026

Synergistic effects of herbal extracts and nanoparticles in skin damage repair: A comprehensive review.

Somaihe Sabzali, Seifollah Bahramikia, Kiana Shahzamani

Abstract readReview
In one paragraph

Review in Avicenna journal of phytomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Somaihe SabzaliAssistant Professor, Department of Biology, Faculty of Basic Sciences, Lorestan University, Khorramabad, Iran.
Seifollah BahramikiaAssociate Professor, Department of Biology, Faculty of Basic Sciences, Lorestan University, Khorramabad, Iran.
Kiana ShahzamaniAssociate Professor, Hepatitis Research Center, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Today, applying herbal extracts to treat skin damage has become widespread and it is supported by numerous studies that confirmed their effectiveness. Due to fewer side effects, diversity of active compounds in them, and lower costs, herbal extracts are an important therapeutic method for skin lesions. Additionally, nanoparticles are important for stimulating the body's ability to recover and treat wounds. Materials and Methods: This review article aims to evaluate how combining herbal extracts with nanoparticles and advanced drug carriers (like liposomes and nanofibers) creates synergistic effects that enhance the treatment of bacterial skin infections and wounds. By improving bioavailability, targeting delivery, and reducing required dosages, these formulated combinations offer a more effective, faster-healing, and potentially safer alternative to conventional therapies. Results: Based on the discussed studies, therapy using a combination of medicinal herbs and nanotechnology increases the effectiveness of treatment, accelerates recovery, and decreases the use of each material, thereby reducing the toxicity of each in infection and skin damage treatment. Conclusion: This review conclusively demonstrates that the strategic formulation of herbal extracts with nanoparticles and advanced drug carriers-such as liposomes, nanofibers, and polymeric nanoparticles-unlocks unprecedented synergistic potential for treating bacterial skin infections and accelerating wound and burn healing. By enhancing bioavailability, enabling targeted delivery, and reducing therapeutic doses (thereby minimizing toxicity), these nano-herbal hybrids represent a paradigm shift toward safer, faster, and more cost-effective regenerative therapies that can combat antibiotic resistance and revolutionize modern dermatological care.

Indexed as

ApplicationFormulated herbal extractsNanoparticleSkin damageTreatment

Identifiers

PMID42770099
PMCPMC13592760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.