Evidence map›Paper›PMID 42770091›Full record

ReviewBurns & trauma2026

Application of electrospun piezoelectric nanofibers in wound healing.

Jing Wang, Jianhua Feng, Chengzhi Zhang, Xiankui Gao, Changjun Jia, Tianming Zhao, Seeram Ramakrishna, Hongye Guan

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Burns & trauma, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jing WangZhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang, People's Republic China.
Jianhua FengZhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang, People's Republic China.
Chengzhi ZhangState Key Laboratory of Robotics and Intelligent Systems, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, 110016, Liaoning, People's Republic China.
Xiankui GaoZhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang, People's Republic China.
Changjun JiaGeneral Education Department, Qilu Medical University, Zibo 255300, Shandong, People's Republic China.
Tianming ZhaoState Key Laboratory of Robotics and Intelligent Systems, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, 110016, Liaoning, People's Republic China.
Seeram RamakrishnaCollege of Design and Engineering, National University of Singapore, Singapore 117575, Singapore.
Hongye GuanZhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang, People's Republic China.ORCID https://orcid.org/0009-0005-7014-6907

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wound healing is essential for maintaining organismal homeostasis and barrier function, posing significant challenges particularly in the management of hard-to-heal wounds such as diabetic ulcers. This review systematically summarizes the functional properties of piezoelectric electrospun biomaterials and their biological mechanisms in promoting wound healing via electrical stimulation (ES). Piezoelectric nanofiber wound dressings fabricated by electrospinning technology offer dual advantages: on one hand, their unique fibrous architecture enables adaptation to irregular wound contours, facilitates rapid hemostasis, and provides an effective barrier against microbial invasion; on the other hand, their inherent piezoelectric effect converts micromechanical deformations into localized electrical signals in real time, thereby modulating cellular behaviors and accelerating tissue repair. This review highlights recent studies elucidating the mechanisms by which ES promotes wound healing, and the functional characteristics of piezoelectric fibrous dressings. It aims to establish a theoretical foundation for the rational design and performance optimization of next-generation intelligent piezoelectric wound dressings, thereby advancing their clinical translation and industrial development.

Indexed as

BiomaterialElectrical stimulationElectrospinningPiezoelectric nanofibersWound healing

Identifiers

PMID42770091
PMCPMC13592679

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.