Evidence map›Paper›PMID 42770034›Full record

ReviewJournal of pain research2026

Effects of Virtual Reality-Based Interventions on Neuropathic Pain in Individuals with Spinal Cord Injury: A Meta-Analysis of Randomized Controlled Trials.

Chang Liu, Yamei Liu

Abstract readReview
In one paragraph

Review in Journal of pain research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Chang LiuDepartment of Rehabilitation Medicine, Yantai Shan Hospital, Yantai, 264000, People's Republic of China.ORCID 0009-0009-8980-7153
Yamei LiuDepartment of Education, Yantai Shan Hospital, Yantai, 264000, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Neuropathic pain is a common and difficult-to-treat complication of spinal cord injury (SCI). Virtual reality (VR)-based interventions have emerged as a non-pharmacological approach to pain modulation, but their efficacy remains uncertain. This meta-analysis evaluated the effect of VR-based interventions on neuropathic pain intensity in individuals with SCI. Methods: PubMed, Cochrane Library, Embase, Web of Science, Wanfang, and CNKI were searched through June 19, 2026. Randomized controlled trials (RCTs) comparing VR-based interventions with control conditions in adults with SCI-related neuropathic pain were included. Standardized mean differences (SMDs) with 95% confidence intervals (CIs) were pooled using a random-effects model accounting for the influence of potential heterogeneity. Results: Ten RCTs involving 317 participants contributed 12 comparisons. VR-based interventions significantly reduced neuropathic pain intensity compared with controls (SMD = -0.50, 95% CI -0.76 to -0.25; Conclusion: VR-based interventions probably reduce neuropathic pain intensity in individuals with SCI. Further well-designed, adequately powered RCTs are warranted to confirm the magnitude and durability of this effect.

Indexed as

meta-analysisneuropathic painrehabilitationspinal cord injuryvirtual reality

Identifiers

PMID42770034
PMCPMC13592339

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.