Evidence map›Paper›PMID 42769900›Full record

ArticleEuropean journal of organic chemistry2026

Metal-Free Ligand-Centered Radical Scavenging in Pyridine-Modified Tetraaza Macrocycles.

Christina Mantsorov, Hannah K Pyle, Tahmina Afroz, Caden-Jack N Walls, Nora Del Bosque, Timothy M Schwartz, Chelsea N Miller, Kristof Pota, Benjamin G Janesko, Kayla N Green

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of organic chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Christina MantsorovDepartment of Chemistry and Biochemistry, Texas Christian University, Fort Worth, Texas, USA.
Hannah K PyleDepartment of Chemistry and Biochemistry, Texas Christian University, Fort Worth, Texas, USA.
Tahmina AfrozDepartment of Chemistry and Biochemistry, Texas Christian University, Fort Worth, Texas, USA.
Caden-Jack N WallsDepartment of Chemistry and Biochemistry, Texas Christian University, Fort Worth, Texas, USA.
Nora Del BosqueDepartment of Chemistry and Biochemistry, Texas Christian University, Fort Worth, Texas, USA.
Timothy M SchwartzDepartment of Chemistry and Biochemistry, Texas Christian University, Fort Worth, Texas, USA.
Chelsea N MillerDepartment of Chemistry and Biochemistry, Texas Christian University, Fort Worth, Texas, USA.
Kristof PotaDepartment of Chemistry and Biochemistry, Texas Christian University, Fort Worth, Texas, USA.
Benjamin G JaneskoDepartment of Chemistry and Biochemistry, Texas Christian University, Fort Worth, Texas, USA.
Kayla N GreenDepartment of Chemistry and Biochemistry, Texas Christian University, Fort Worth, Texas, USA.ORCID 0000-0001-8816-7646

Funding

Targeting oxidative stress in neurodegeneration using pyridol-derived small moleculesR15GM123463 · NIGMS · TEXAS CHRISTIAN UNIVERSITY · PI AKKARAJU, GIRIDHAR, CHUMLEY, MICHAEL J · 2018 to 2025
$1.2M
NIGMS NIH HHS R15 GM123463
6 · The paper itself

Abstract

Pyridine-modified tetraaza macrocycles are widely studied as ligand platforms for metal coordination, yet their intrinsic redox and radical reactivity in the absence of metals remains unclear. Here, we report the unexpected finding that pyridinophane Py

Indexed as

chemistrydelocalized electrondensity functional theoryDPPHfree radical scavengerligandpyridinophaneradicalredoxsubstituent

Identifiers

PMID42769900
PMCPMC13593359

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.