Evidence map›Paper›PMID 42769877›Full record

ReviewFrontiers in microbiology2026

Characteristics of gut microbiota dysbiosis in patients with depression: a visual analysis of knowledge maps.

Chenggui Xu, Shouyao Zhang, Yong Liao, Exian Shan, Pengbin Zhao, Ruilu Liu, Jiayu Wang, Minjie Yin, Xiantao Tai, Xinghe Zhang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chenggui Xu *The Second Clinical Medical School, Yunnan University of Chinese Medicine, Kunming, China.
Shouyao Zhang *The First Clinical Medical School, Yunnan University of Chinese Medicine, Kunming, China.
Yong LiaoThe Second Clinical Medical School, Yunnan University of Chinese Medicine, Kunming, China.
Exian ShanThe Second Clinical Medical School, Yunnan University of Chinese Medicine, Kunming, China.
Pengbin ZhaoThe Second Clinical Medical School, Yunnan University of Chinese Medicine, Kunming, China.
Ruilu LiuThe Second Clinical Medical School, Yunnan University of Chinese Medicine, Kunming, China.
Jiayu WangThe Second Clinical Medical School, Yunnan University of Chinese Medicine, Kunming, China.
Minjie YinThe Second Clinical Medical School, Yunnan University of Chinese Medicine, Kunming, China.
Xiantao TaiThe Second Clinical Medical School, Yunnan University of Chinese Medicine, Kunming, China.
Xinghe ZhangThe Second Clinical Medical School, Yunnan University of Chinese Medicine, Kunming, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients with depression exhibit significant gut microbiota dysbiosis; however, visualized studies into dysbiosis-related microbial signatures in depression remain limited. To identify characteristic differential genera in depressed individuals, this study adopted a knowledge graph-based visualization analysis to clarify the associations between intestinal microbial dysbiosis and depression. Methods: A search strategy was constructed and literature searches were conducted in 7 databases, including Web of Science, PubMed, Scopus, Cochrane Library, CNKI, Wanfang Database and VIP Net (VIP). The search cutoff date was April 1, 2026. The included literature was strictly screened according to the PRISMA guidelines. EndNote 25 was used to sort and trace the literature meeting the inclusion criteria. GRADE system, Cochrane ROB2.0, and JBI scale were used for quality evaluation and evidence grading of RCTs and cross-sectional studies. Results: A total of 159 valid studies from 21 countries were ultimately included, involving 25310 patients with depression. The bacterial community taxa predominantly consisted of Conclusion: Dysbiosis in patients with depression was characterized by markedly decreased abundances of protective microbes including

Indexed as

bacteriadepressiongut microbiotaknowledge mapreview

Identifiers

PMID42769877
PMCPMC13591385

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.