Evidence map›Paper›PMID 42769851›Full record

ArticleOncology research2026

DNA Polymerase θ Drives Colorectal Cancer Progression through Wnt/β-Catenin Activation and Shows Potential Association with Immunosuppressive Microenvironment Remodeling.

Li Li, Jianhua Wang, Feilong Zhou, Lingjun Geng, Kongwang Hu

Abstract read
In one paragraph

Article in Oncology research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Li LiDepartment of General Surgery, The Fifth Affiliated Hospital of Anhui Medical University, Fuyang, China.
Jianhua WangDepartment of General Surgery, The Fifth Affiliated Hospital of Anhui Medical University, Fuyang, China.
Feilong ZhouDepartment of General Surgery, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Lingjun GengDepartment of General Surgery, The Fifth Affiliated Hospital of Anhui Medical University, Fuyang, China.
Kongwang HuDepartment of General Surgery, The Fifth Affiliated Hospital of Anhui Medical University, Fuyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

beta CateninColorectal NeoplasmsDNA-Directed DNA PolymeraseTumor MicroenvironmentWnt Signaling PathwayAnimalsCell Line, TumorCell MovementCell ProliferationDisease ProgressionDNA Polymerase thetaEpithelial-Mesenchymal TransitionFemaleGene Expression Regulation, NeoplasticHumansMalebeta CateninDNA-Directed DNA PolymeraseDNA Polymerase thetacolorectal cancerepithelial-mesenchymal transition (EMT)POLQ (DNA polymerase theta)tumor microenvironmentWnt/β-catenin signaling

Identifiers

PMID42769851
PMCPMC13591362

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.