Evidence map›Paper›PMID 42769811›Full record

ReviewFrontiers in microbiology2026

Quorum sensing in oral multispecies biofilms: from interkingdom communication to therapeutic targeting.

Yeping Lu, Yichao Xia, Jie Zhang, Fangyong Zhu, Zelda Ziyi Zhao

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yeping Lu *Department of Stomatology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Yichao Xia *Department of Stomatology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Jie ZhangDepartment of Stomatology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Fangyong ZhuDepartment of Stomatology, Affiliated Hospital of Jiangnan University, Wuxi, China.
Zelda Ziyi ZhaoDepartment of Stomatology, Affiliated Hospital of Jiangnan University, Wuxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral biofilms are polymicrobial ecosystems where quorum sensing (QS) governs community assembly, virulence and homeostasis. This narrative review synthesizes evidence on QS pathways in key periodontal and cariogenic pathogens, emphasizing interspecies synergy, cross-kingdom interactions, and disease progression. We surveyed English-language publications up to 2026 across PubMed, Web of Science, and Scopus. Our analysis reveals three major QS circuits: the widely conserved LuxS/AI-2 system facilitating cooperative and competitive behaviors, such as

Indexed as

microbial interactionoral biofilmperiodontitisquorum quenchingquorum sensing

Identifiers

PMID42769811
PMCPMC13591311

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.