Evidence map›Paper›PMID 42769695›Full record

ArticlePediatric gastroenterology, hepatology & nutrition2026

Use of Noninvasive Biomarker Tests vs. FibroScan for Predicting Significant Fibrosis in Egyptian Pediatric Cancer Survivors with Chronic Hepatitis C Virus Infection.

Dalia N Toaima, Fatma A Marzouk, Alaa El-Haddad, Aisha Elsharkawy, Gamal E Esmat, Manal H El-Sayed

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Article in Pediatric gastroenterology, hepatology & nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dalia N ToaimaDepartment of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt.ORCID https://orcid.org/0000-0002-0033-4217
Fatma A MarzoukDepartment of Pediatrics, Ministry of Health Hospitals, Cairo, Egypt.ORCID https://orcid.org/0009-0000-9145-1154
Alaa El-HaddadDepartment of Pediatric Oncology, National Cancer Institute, Cairo, Egypt.ORCID https://orcid.org/0000-0003-3538-5038
Aisha ElsharkawyDepartment of Tropical Medicine, Faculty of Medicine, Cairo University, Cairo, Egypt.ORCID https://orcid.org/0000-0002-7150-173X
Gamal E EsmatDepartment of Tropical Medicine, Faculty of Medicine, Cairo University, Cairo, Egypt.ORCID https://orcid.org/0000-0001-8614-1629
Manal H El-SayedDepartment of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt.ORCID https://orcid.org/0000-0002-6613-0276

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Egyptian children undergoing chemotherapy are at high risk of hepatitis C virus (HCV) infection because of immunosuppression and multiple blood transfusions. This study evaluated liver fibrosis by comparing transient elastography with aminotransferase-to-platelet ratio index (APRI) and fibrosis index based on four factors (FIB-4) in pediatric cancer survivors with chronic HCV infection. Fifty-one cancer survivors with chronic HCV infection (median age, 13.5 years) were prospectively recruited from the pediatric oncology and hepatology clinics at Ain Shams University and the National Cancer Institute. All participants underwent noninvasive fibrosis assessment using transient elastography, APRI, and FIB-4, as well as liver function testing, ultrasonography, and liver biopsy when necessary. Based on liver stiffness measurements, patients were classified into group 1 (fibrosis stage F0-F2; 80.4%) or group 2 (fibrosis stage F3-F4; 19.6%). Compared with group 1, group 2 had significantly higher serum bilirubin and alanine aminotransferase (ALT) levels, lower platelet counts, and higher APRI and FIB-4 scores (

Indexed as

Aspartate aminotrans-ferase-to-platelet-ratio indexCancer survivorsElastographyFibrosis index based on four factorsHepatitis CLiver stiffness

Identifiers

PMID42769695
PMCPMC13591162

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.