Evidence map›Paper›PMID 42769649›Full record

ArticleBiomedical optics express2026

Multi-frequency asynchronous optical coherence elastography by direct demodulation.

Ginger Schmidt, Ryan McAuley, Brett E Bouma, Néstor Uribe-Patarroyo

Abstract read
In one paragraph

Article in Biomedical optics express, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ginger SchmidtWellman Center for Photomedicine, Harvard Medical School and Massachusetts General Hospital, 40 Blossom Street, Boston, Massachusetts 02114, USA.ORCID https://orcid.org/0000-0003-4373-3266
Ryan McAuleyWellman Center for Photomedicine, Harvard Medical School and Massachusetts General Hospital, 40 Blossom Street, Boston, Massachusetts 02114, USA.
Brett E BoumaWellman Center for Photomedicine, Harvard Medical School and Massachusetts General Hospital, 40 Blossom Street, Boston, Massachusetts 02114, USA.
Néstor Uribe-PatarroyoWellman Center for Photomedicine, Harvard Medical School and Massachusetts General Hospital, 40 Blossom Street, Boston, Massachusetts 02114, USA.ORCID https://orcid.org/0000-0001-9201-2196

Funding

TRD3: Percutaneous and Interstitial ImagingP41EB015903 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Brett E Bouma · 2012 to 2026
$22.4M
Intravascular microstructural, chemical and biomechanical characterization of coronary plaquesR01EB033306 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI URIBE-PATARROYO, NESTOR · 2022 to 2025
$2.5M
NIBIB NIH HHS P41 EB015903NIBIB NIH HHS R01 EB033306
6 · The paper itself

Abstract

Optical coherence elastography has demonstrated promising results in highly specialized, research-grade OCT systems and in systems with custom, slow scan patterns. However, these approaches are fundamentally incompatible with commercial, FDA-approved OCT systems already deployed in clinics worldwide. Asynchronous optical coherence elastography addresses this limitation by using raster scanning-induced amplitude modulation to spatially encode harmonic shear wave displacement fields. This principle enables recovery of the coherent shear wave field within seconds using conventional frame-rate systems, despite severe temporal undersampling across B-scans. In this work, we extend this approach to show that asynchronous imaging can recover multiple simultaneous excitation frequencies, effectively multiplexing the determination of shear wave dispersion curves. We further introduce a new recovery framework, termed

Identifiers

PMID42769649
PMCPMC13592244

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.