Evidence map›Paper›PMID 42769569›Full record

ReviewFrontiers in transplantation2026

Advancements in

Danae G Olaso, Victoria A Bendersky, Wyeth D Alexander, Aleah L Brubaker, Peter A Than, Gabriel T Schnickel

Abstract readReview
In one paragraph

Review in Frontiers in transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Danae G OlasoDivision of Transplantation and Hepatobiliary Surgery, Department of Surgery, University of California San Diego, La Jolla, CA, United States.
Victoria A BenderskyDivision of Transplantation and Hepatobiliary Surgery, Department of Surgery, University of California San Diego, La Jolla, CA, United States.
Wyeth D AlexanderDivision of Transplantation and Hepatobiliary Surgery, Department of Surgery, University of California San Diego, La Jolla, CA, United States.
Aleah L BrubakerDivision of Transplantation and Hepatobiliary Surgery, Department of Surgery, University of California San Diego, La Jolla, CA, United States.
Peter A ThanDivision of Transplantation and Hepatobiliary Surgery, Department of Surgery, University of California San Diego, La Jolla, CA, United States.
Gabriel T SchnickelDivision of Transplantation and Hepatobiliary Surgery, Department of Surgery, University of California San Diego, La Jolla, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Organ transplantation remains the definitive treatment for end-stage organ failure, yet its impact continues to be constrained by a persistent shortage of suitable donor organs. Despite advances in surgical technique, immunosuppression, and recipient management, organ preservation has remained relatively unchanged for decades. Machine perfusion (MP) has emerged as a transformative advancement in organ preservation, shifting the paradigm from passive storage to active organ support. By actively circulating perfusate under controlled conditions, MP enables metabolic support, mitigation of ischemic injury, and functional assessment prior to implantation. These modalities collectively represent a paradigm shift from passive preservation toward active resuscitation and repair. This review synthesizes current advances in MP across abdominal organ transplantation, emphasizing the scientific rationale, technical evolution, organ-specific applications, and translational challenges. By examining key clinical trials, emerging biomarkers, and future directions we aim to delineate the roadmap for integrating MP into routine clinical practice and realize its full potential in expanding the donor pool and improving graft outcomes.

Indexed as

hypothermicmachine perfusion (MP)normothermicorgan transplantperfusion

Identifiers

PMID42769569
PMCPMC13591775

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.