ArticleAmerican journal of translational research2026
Efficacy of goserelin combined with laparoscopic surgery for endometriosis and its effects on ovarian function and oxidative stress.
Article in American journal of translational research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo investigate the efficacy of goserelin (GOS) combined with laparoscopic surgery (LS) in the treatment of endometriosis (EMS), and its effects on ovarian function and oxidative stress (OS).
methodsA total of 208 patients with EMS were enrolled in this retrospective study. The control group (n=102) received LS alone, while the research group (n=106) received GOS combined with LS. The endpoints included therapeutic efficacy, time to ovulation resumption, time to menstrual recovery, dysmenorrhea, pelvic pain, ovarian function indices [follicle-stimulating hormone (FSH), estradiol (E
resultsCompared to the control group, the research group showed the following significant differences: (1) The total effective rate was notably higher, and the time to ovulation resumption and menstrual recovery was significantly shorter; (2) Postoperative dysmenorrhea and pelvic pain were evidently relieved, and the postoperative levels of FSH, E
conclusionOn the basis of LS, the addition of GOS is effective for the treatment of EMS, and it exerts positive effects on improving ovarian function and inhibiting OS.
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