Trial reportFrontiers in surgery2026
Dexmedetomidine vs. midazolam at single low doses for opioid and muscle relaxant-free anesthesia in pediatric dentistry: a randomized control trial.
Trial report in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: To verify whether a single low dose of dexmedetomidine could reduce emergence agitation (EA) among pediatric dental patients undergoing outpatient general anesthesia in a clinical dental setting. Study design: Prospective randomized clinical trial. Methods: This study included 90 children scheduled for elective dental procedures. Patients were randomly assigned to three groups: midazolam (MID, 0.02 mg/kg, Results: The incidence of EA in the DEX group was significantly lower than that in the saline group, while the incidence in the Mid group showed no significant difference compared with the other two groups after a Bonferroni correction. The three groups showed statistically significant differences in TOW recovery time, with the DEX group having the longest, the Mid group intermediate, and the saline group the shortest. Conclusion: A single low dose of dexmedetomidine at induction significantly reduces EA in pediatric dental outpatients, without compromising day-surgery discharge feasibility despite a modest prolongation of recovery time. Clinical Trial Registration: https://www.chictr.org.cn/showproj.html?proj=215673.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.