ArticleAmerican journal of translational research2026
Diuretic resistance during emergency treatment of acute heart failure: incidence and correlation with 30-day readmission.
Article in American journal of translational research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesTo investigate the incidence of diuretic resistance (DR) during emergency treatment of acute heart failure (AHF) and its correlation with 30-day readmission.
methodsWe retrospectively collected data from 198 AHF patients admitted to Beijing Chao-Yang Hospital, Capital Medical University between 2021 and 2025. Patients were allocated into a DR group and non-DR group according to the presence of diuretic resistance. Baseline characteristics, laboratory values, echocardiographic indices, and readmission rate were compared between the two groups. Logistic regression was performed to analyze the correlation between DR and short-term readmission rate. A nomogram was constructed to develop a clinical prediction model for readmission, and SHapley Additive exPlanations (SHAP) were used for model interpretation.
resultsDR occurred in 48 patients (24.24%). The 30-day readmission rate was higher in the DR group than in the non-DR group (37.5% vs. 18.0%,
conclusionsThe incidence of DR in AHF patients during emergency treatment is closely associated with an increased risk of 30-day readmission. Early identification and intervention for DR may improve short-term prognosis.
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