Evidence map›Paper›PMID 42769255›Full record

SynthesisFrontiers in aging neuroscience2026

Age-related cortical mechanisms underlying postural control: a systematic review.

Myeongjin Bae, Alexandria Hoang, Katarina Puš, Valerie Nunez, Uros Marusic, Jeannette R Mahoney

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in aging neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Myeongjin BaeDivision of Cognitive and Sensorimotor Aging, Department of Neurology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, United States.
Alexandria HoangDepartment of Neurobiology and Behavior, Stony Brook University, Stony Brook, NY, United States.
Katarina PušInstitute for Kinesiology Research, Science and Research Centre Koper, Koper, Slovenia.
Valerie NunezDivision of Cognitive and Sensorimotor Aging, Department of Neurology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, United States.
Uros MarusicDivision of Cognitive and Sensorimotor Aging, Department of Neurology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, United States.
Jeannette R MahoneyDivision of Cognitive and Sensorimotor Aging, Department of Neurology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, United States.

Funding

Visual-somatosensory integration as a novel marker of Alzheimer's diseaseR01AG075679 · NIA · STATE UNIVERSITY NEW YORK STONY BROOK · PI Jeannette R. Mahoney · 2022 to 2026
$3.7M
NIA NIH HHS R01 AG075679
6 · The paper itself

Abstract

Introduction: Despite growing interest in age-related cortical mechanisms of postural control, heterogeneity across studies has limited the synthesis of existing evidence. This systematic review aimed to (1) characterize age-related alterations in cortical activity during standing balance tasks with sensory, cognitive, and mechanical challenges; (2) examine the association between cortical activity and postural sway; and (3) characterize the current methodology of assessing cortical activity during standing balance tasks in older adults (OA). Methods: Relevant research articles were identified through systematic searches of MEDLINE, EMBASE, PsycINFO, and CINAHL from inception to October 8, 2025. Eligible studies measured cortical activity during standing balance under sensory, cognitive, and mechanical challenges using electroencephalography (EEG) or functional near-infrared spectroscopy (fNIRS). We used the Standard Quality Assessment Criteria for quantitative studies for quality assessment. Results: Thirty-seven studies with a total of 1,302 participants, including 788 OA (60.5%), were included. Most studies ( Discussion: This systematic review indicates that aging may be associated with diminished task-dependent cortical modulation, weaker associations between cortical activity and postural sway, and delayed sensorimotor processing during challenging balance tasks. These findings provide a foundation for future studies aimed at clarifying age-related cortical mechanisms of postural control during standing balance. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/, identifier CRD420251159695.

Indexed as

agingcortical activationdual-taskmechanical perturbationpostural balancereactive balancesensory perturbationstatic balance

Identifiers

PMID42769255
PMCPMC13590551

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.