ArticleAmerican journal of translational research2026
Effects of inhalation anesthesia with sevoflurane combined with oxygen inhalation on cerebral oxygen metabolism and cognitive function in lung cancer patients undergoing unilateral lung ventilation.
Article in American journal of translational research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveThis study evaluated the effects of sevoflurane inhalation anesthesia on cerebral oxygenation and neurocognitive function during one-lung ventilation for lung cancer surgery.
methodsThis retrospective study included 109 patients with lung cancer who underwent unilateral lung ventilation. Patients were divided into a propofol group (n=54) and a sevoflurane group (n=55) according to the anesthesia protocol. Hemodynamic parameters, cerebral oxygen metabolism, anesthesia recovery times, cognitive function, and pulmonary function were assessed.
resultsCompared with the propofol group, the sevoflurane group had significantly lower heart rate (HR) and mean arterial pressure (MAP) at 15 minutes before surgery and immediately after surgery (
conclusionSevoflurane inhalation anesthesia can improve cerebral oxygen metabolism, accelerate the post-anesthesia recovery process, and enhance pulmonary function in patients undergoing one-lung ventilation for lung cancer surgery compared with propofol, but it is also associated with a higher risk of postoperative cognitive dysfunction at 24 hours after surgery.
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