ArticleInternational journal of nanomedicine2026
ROS-Scavenging Hyperbranched Polymer Dot Nanozymes Combined with Fractional CO
Article in International journal of nanomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: Topical nanomaterials for hair regeneration are limited by poor follicular penetration, while the regenerative window opened by fractional laser injury is transient and accompanied by rep air-constraining oxidative stress. We investigated whether fractional CO Patients and Methods: HPD (3-5 nm), synthesized by A Results: Optimized irradiation (30 mJ, 196 spots cm Conclusion: Laser microchannels act as both delivery portals and regenerative triggers, while HPD scavenges post-injury reactive oxygen species and sustains Wnt/β-catenin activation, producing a greater-than-additive acceleration of hair follicle regeneration exceeding minoxidil. This reflects activation and accelerated growth of existing follicles rather than de novo neogenesis, and offers a drug-free platform for regenerative dermatology.
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