Evidence map›Paper›PMID 42768738›Full record

ReviewCancer medicine2026

Cancer Stem Cell Quiescence: Molecular and Microenvironmental Evidence for an Actively Regulated Adaptive Survival Strategy.

Yasin Ahmadi, Trefa M Abdullah, Sakhavat Abolhasani, Amin Jalizi

Abstract readReview
In one paragraph

Review in Cancer medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yasin AhmadiDepartment of Medical Laboratory Science, Komar University of Sciences and Technology, Sulaymaniyah, Kurdistan Region, Iraq.ORCID https://orcid.org/0000-0001-6721-1775
Trefa M AbdullahDepartment of Basic Science, College of Pharmacy, University of Sulaimani, Sulaymaniyah, Kurdistan Region, Iraq.ORCID https://orcid.org/0000-0002-2026-1617
Sakhavat AbolhasaniDepartment of Basic Sciences and Health, Sarab Faculty of Medical Sciences, Sarab, East Azerbaijan, Iran.ORCID https://orcid.org/0000-0001-9888-7508
Amin JaliziDepartment of Basic Sciences and Health, Sarab Faculty of Medical Sciences, Sarab, East Azerbaijan, Iran.ORCID https://orcid.org/0009-0004-1095-8906

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer stem cells (CSCs) are a therapy-refractory subpopulation that drives tumor persistence, recurrence, and metastasis. A defining characteristic of CSCs is their ability to reversibly exit the cell cycle and enter a quiescent state, thereby escaping cytotoxic therapies that primarily target proliferating cells. Although numerous reviews have examined CSC dormancy and quiescence, less attention has been devoted to recently identified regulators and to the molecular events associated with the transition into quiescence. This narrative review consolidates current knowledge on CSC-specific entry regulators, including the pRb/RBL2-E2F1/4-GCN5 axis, Fbxw7-c-Myc pathway, PML-PPARδ-FAO axis, ID1/ID3-p21 network, JARID1B-mediated G

Indexed as

NeoplasmsNeoplastic Stem CellsTumor MicroenvironmentAnimalsCell CycleCell SurvivalEpigenesis, GeneticHumansSignal Transductioncancer stem cellcellular exhaustiondormancyquiescencetherapy resistancetumor microenvironment

Identifiers

PMID42768738
PMCPMC13594564

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.