ArticleBulletin of experimental biology and medicine2026
Neuronal Activity Rapidly Decreases the Level of p53 Protein in Rat Hippocampus In Vivo.
Article in Bulletin of experimental biology and medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It was previously shown that the induction of long-term post-tetanic potentiation of synaptic transmission in rat hippocampal slices is accompanied by a rapid decrease in the levels of the transcription factor p53 (tumor suppressor p53). However, it remained unclear whether a similar phenomenon could be observed in vivo. To answer this question, we employed a pentylenetetrazole (PTZ)-induced seizure model in rats. At 20 and 40 min after an intraperitoneal injection of PTZ, hippocampal p53 levels were significantly reduced compared to the intact controls. These findings validate the data previously obtained in vitro.
Indexed as
Identifiers
42768256What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.