Evidence map›Paper›PMID 42768205›Full record

ArticleAesthetic plastic surgery2026

Intramuscular Fat Grafting for Pectoralis Volumization in Transmasculine Patients. Combining Chest Masculinization and Chest Contouring in One Surgery.

C V Brasó, C Corrao, R Elia, M Maruccia, G Giudice

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Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

C V BrasóClinica Brasó, Hospital General De Catalunya, Carrer de Pedro i Pons, 08195, Sant Cugat del Vallès, Barcelona, Spain.
C CorraoDivision of Plastic and Reconstructive Surgery, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari Aldo Moro, Piazza Giulio Cesare, 70121, Bari, Italy. Claudia.corrao05@gmail.com.ORCID http://orcid.org/0009-0002-5600-3692
R EliaDivision of Plastic and Reconstructive Surgery, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari Aldo Moro, Piazza Giulio Cesare, 70121, Bari, Italy.
M MarucciaDivision of Plastic and Reconstructive Surgery, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari Aldo Moro, Piazza Giulio Cesare, 70121, Bari, Italy.
G GiudiceDivision of Plastic and Reconstructive Surgery, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari Aldo Moro, Piazza Giulio Cesare, 70121, Bari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChest masculinization surgery represents a key component of gender-affirming care for transgender men and has been associated with significant improvements in psychological well-being and reduction of gender dysphoria. Although established techniques such as double-incision mastectomy with nipple-areola complex grafting and periareolar approaches effectively remove breast tissue, postoperative chest contour may remain flat and lack pectoral definition in some patients. Autologous fat grafting has been widely used in cisgender male aesthetic surgery to enhance pectoral projection and muscular definition. However, its application during masculinizing mastectomy in transgender patients remains poorly described. This study evaluates the outcomes and safety of intramuscular pectoralis major fat grafting performed concurrently with chest masculinization surgery.

methodsA retrospective analysis of prospectively collected data was conducted on transgender patients who underwent chest masculinization surgery with simultaneous pectoralis major fat grafting between January 2022 and January 2025 at a single institution. Patients underwent either double-incision mastectomy with free nipple-areola complex grafting or ultrasonic-assisted subcutaneous mastectomy depending on breast characteristics. Autologous fat was harvested from the flanks, axillary pillar, or back and injected into the pectoralis major muscle in intramuscular and sub-muscular planes. Primary outcomes included patient satisfaction assessed at 12 months using the validated TRANS-Q questionnaire. Secondary outcomes included postoperative complications and revision procedures classified according to the Clavien-Dindo system.

resultsSixty transgender patients (120 mastectomies) were included. The mean age was 32.5 years, and the mean body mass index was 22.5 kg/m

conclusionsIntramuscular pectoralis major fat grafting combined with chest masculinization surgery appears to be a safe and effective strategy to enhance thoracic contour and improve masculine chest definition in transgender men. This integrated approach may optimize aesthetic outcomes and contribute to high levels of patient satisfaction and gender congruence. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

Chest contouringFat graftingGender affirming surgeryMastectomyPectoralis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.