Evidence map›Paper›PMID 42767669›Full record

ArticleClinical transplantation2026

Dual versus Single Kidney Transplantation in Contemporary U.S. Practice: A National Matched Cohort Study.

Abdulghani Abou Koura, Alex Judd, Stephanie Silpe, Juan F Guerra, Danielle Ladie, Kenneth Brayman, Shawn J Pelletier, Yazan Al-Adwan

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Abdulghani Abou KouraDepartment of Surgery, Division of Transplantation, University Of Virginia Health System, Charlottesville, Virginia, USA.
Alex JuddDepartment of Surgery, Division of Transplantation, University Of Virginia Health System, Charlottesville, Virginia, USA.
Stephanie SilpeDepartment of Surgery, Division of Transplantation, University Of Virginia Health System, Charlottesville, Virginia, USA.
Juan F GuerraDepartment of Surgery, Division of Transplantation, University Of Virginia Health System, Charlottesville, Virginia, USA.
Danielle LadieDepartment of Surgery, Division of Transplantation, University Of Virginia Health System, Charlottesville, Virginia, USA.
Kenneth BraymanDepartment of Surgery, Division of Transplantation, University Of Virginia Health System, Charlottesville, Virginia, USA.
Shawn J PelletierDepartment of Surgery, Division of Transplantation, University Of Virginia Health System, Charlottesville, Virginia, USA.
Yazan Al-AdwanDepartment of Surgery, Division of Transplantation, University Of Virginia Health System, Charlottesville, Virginia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHard-to-place kidneys remain underutilized despite ongoing organ shortage. Dual kidney transplantation (DKT) may improve use of these grafts, but contemporary national data are limited.

methodsWe performed a retrospective cohort study using national databases from March 2015 to December 2024. Outcomes after DKT and single kidney transplantation (SKT) were compared in the overall cohort and after 2:1 propensity score matching (PSM) using Kaplan-Meier, Cox, and logistic regression.

resultsA total of 140,707 deceased donor kidney transplants were analyzed, including 1,236 (0.9%) DKT. In the overall cohort, DKT was associated with lower graft and patient survival. After 2:1 PSM, 1,105 DKT recipients were matched to 2,210 SKT recipients with balanced recipient age (63.7 vs 63.9 years) and KDPI (75.5 vs 75.8; SMD <0.03). After PSM, DKT was associated with higher 1-, 3-, and 5-year graft survival (92.2%, 81.8%, and 69.8% vs 87.7%, 75.5%, and 59.9%; all P < 0.001), while DGF rates were similar.

conclusionDKT remains an uncommon but important strategy for utilization of hard-to-place donor kidneys. After matching recipients with comparable age and KDPI, DKT was associated with favorable graft and patient survival and similar DGF rates, supporting selective use in carefully chosen recipients.

Indexed as

Graft RejectionGraft SurvivalKidney Failure, ChronicKidney TransplantationPostoperative ComplicationsTissue and Organ ProcurementTissue DonorsFemaleFollow-Up StudiesGlomerular Filtration RateHumansKidney Function TestsMaleMiddle AgedPrognosisPropensity Scoredelayed graft functiongraft survivalkidney transplantation

Identifiers

PMID42767669
PMCPMC13593390

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.