Evidence map›Paper›PMID 42767182›Full record

ReviewPoultry science2026

Advances in RNA m6A modification research and its role in poultry economic traits.

Jing Liu, Haodong Liu, Xuwen Huang, Zhixiang Xiao, Site Li, Xiaolong Hu, Sanfeng Liu, Huirong Mao, Biao Chen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Poultry science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jing LiuCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, Jiangxi, 330045, China; Poultry Institute, Jiangxi Agricultural University, Nanchang, 330045, China.
Haodong LiuCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, Jiangxi, 330045, China; Poultry Institute, Jiangxi Agricultural University, Nanchang, 330045, China.
Xuwen HuangCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, Jiangxi, 330045, China; Poultry Institute, Jiangxi Agricultural University, Nanchang, 330045, China.
Zhixiang XiaoCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, Jiangxi, 330045, China; Poultry Institute, Jiangxi Agricultural University, Nanchang, 330045, China.
Site LiCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, Jiangxi, 330045, China.
Xiaolong HuCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, Jiangxi, 330045, China; Poultry Institute, Jiangxi Agricultural University, Nanchang, 330045, China.
Sanfeng LiuCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, Jiangxi, 330045, China; Poultry Institute, Jiangxi Agricultural University, Nanchang, 330045, China.
Huirong MaoCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, Jiangxi, 330045, China; Poultry Institute, Jiangxi Agricultural University, Nanchang, 330045, China. Electronic address: huirongm82@126.com.
Biao ChenCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, Jiangxi, 330045, China; Poultry Institute, Jiangxi Agricultural University, Nanchang, 330045, China. Electronic address: chenbiao@jxau.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N6-methyladenosine (m6A) is the most abundant and evolutionarily conserved internal epitranscriptomic modification on eukaryotic mRNA, playing pivotal roles in animal growth, development, metabolism, and immune responses by modulating mRNA splicing, stability, and translation efficiency. With advancements in technologies such as MeRIP-seq, GLORI-seq, and Nanopore direct RNA sequencing, researchers can now characterize the dynamic landscape of m6A modifications at the transcriptome-wide level. This review summarizes the fundamental features of m6A modifications, compares various detection methods and computational analytical approaches, and critically synthesizes recent progress on the roles of m6A modifications in poultry skeletal muscle development, adipose deposition, reproduction, and immunity and disease resistance. Particular emphasis is placed on the regulatory mechanisms of key enzymes, including METTL3/14, FTO, ALKBH5, and the YTHDF protein family. The potential applications, prospects and current limits of RNA m6A modification as a molecular breeding tool in poultry are also discussed.

Indexed as

Detection methodsDifferentially m6A-modified genesm6A-modifying enzymesPoultry economic traitsRNA m6A modification

Identifiers

PMID42767182

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.