Evidence map›Paper›PMID 42766820›Full record

ArticleBiopsychosocial science and medicine2026

Psychological Resilience to Trauma and Risk of Metabolic Syndrome in Women.

Alexandra Hillcoat, Arielle A J Scoglio, Kelsey N Serier, Andrea L Roberts, Karestan C Koenen, Yang-Yu Liu, Jakob Hartmann, Laksana Rachman, Laura D Kubzansky

Abstract read
In one paragraph

Article in Biopsychosocial science and medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexandra HillcoatORCID 0000-0002-2697-3236
Arielle A J Scoglio
Karestan C KoenenORCID 0000-0003-2978-7655
Laksana Rachman
Laura D KubzanskyORCID 0000-0002-4039-2235

Funding

Life Course Cancer Epidemiology Cohort in WomenU01CA176726 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI ELIASSEN, A. HEATHER, WILLETT, WALTER C. · 2018 to 2025
$22.4M
Integrating lifecourse approaches, biologic and digital phenotypes in support of heart and lung disease epidemiologic researchU01HL145386 · NHLBI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI CHAVARRO, JORGE EDUARDO, MANSON, JOANN ELISABETH · 2019 to 2025
$17.8M
Post Traumatic Stress Disorder and Accelerated Aging in WomenR01MH101269 · NIMH · HARVARD SCHOOL OF PUBLIC HEALTH · PI KOENEN, KARESTAN C, KUBZANSKY, LAURA D · 2014 to 2021
$6.5M
Genetic Determinants of PTSD in WomenR01MH078928 · NIMH · HARVARD SCHOOL OF PUBLIC HEALTH · PI KOENEN, KARESTAN C · 2007 to 2010
$2.9M
Longitudinal Associations of Posttraumatic Stress Disorder with Incident Type 2 Diabetes and Poor Glycemic Control in a Large National CohortK08DK138296 · NIDDK · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Kelsey Nicole Serier · 2024 to 2026
$498k
NCI NIH HHS U01 CA176726NHLBI NIH HHS U01 HL145386NIDDK NIH HHS K08 DK138296NIMH NIH HHS R01 MH078928NIMH NIH HHS R01 MH101269
6 · The paper itself

Abstract

objectivePrevious research suggests an association between posttraumatic stress disorder (PTSD) and metabolic syndrome (MetS) but has not disentangled effects of trauma exposure, PTSD, and psychological resilience following trauma. This study investigated risk of MetS by psychological resilience following trauma exposure.

methodsData are from 42,425 women in the Nurses' Health Study II who completed a survey in 2008 evaluating PTSD symptoms, psychological distress, facets of positive psychological well-being (PWB), and a broad range of covariates. Psychological resilience to trauma was characterized as: resilient (no PTSD and high positive PWB), coping without thriving (no PTSD and low positive PWB), and PTSD, with a no trauma control group. Probable MetS was derived using data on weight, height, diagnosed hypertension, hyperlipidemia, and diabetes, and medication use from biennial surveys between 1989-2019. Time to probable MetS was approximated as the return date of the first questionnaire at which 3+ probable MetS criteria were met.

resultsProportional hazards models adjusted for sociodemographic characteristics indicated that, relative to women with no trauma, women categorized as having PTSD (aHR=1.34 [1.05, 1.71]) or as coping without thriving (aHR=1.29 [1.03, 1.62]) experienced a greater hazard of developing MetS, whereas resilient women experienced a similar hazard of developing MetS (aHR=1.06 [0.84, 1.34]). Results remained similar after adjusting for health behaviors and antidepressant use.

conclusionsFuture research on trauma and MetS should consider varied trauma responses and assess if interventions that not only reduce psychological distress but also promote PWB could mitigate MetS risk.

Indexed as

metabolic syndromenurses’ health studypsychological well-beingPTSDresiliencetrauma

Identifiers

PMID42766820
PMCPMC13662864

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.