Evidence map›Paper›PMID 42766636›Full record

ArticleJMIR formative research2026

Learning the Capacity to Feel Better Through Experiment in a Box (XB): Qualitative Interpretive Description and Prototheory Development of Tuning.

Steven A De La Torre, Richard Gomer, Eric Hekler, M C Schraefel

Abstract read
In one paragraph

Article in JMIR formative research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Steven A De La TorreHerbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, San Diego, CA, United States.ORCID 0000-0002-3303-8270
Richard GomerSchool of Electronics and Computer Science, University of Southampton, Southampton, United Kingdom.ORCID 0000-0001-8866-3738
Eric HeklerHerbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, San Diego, CA, United States.ORCID 0000-0002-7434-0775
M C SchraefelWellthLab, Electronics and Computer Science, University of Southampton, Southampton, United Kingdom.ORCID 0000-0002-9061-7957

Funding

Optimizing Individualized and Adaptive mHealth Interventions via Control Systems Engineering MethodsR01CA244777 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HEKLER, ERIC, RIVERA, DANIEL E · 2020 to 2024
$3.8M
NCI NIH HHS R01 CA244777
6 · The paper itself

Abstract

Background: Experiment in a Box (XB) is a guided, time-limited framework designed to help individuals test and adapt simple eating and movement heuristics within the context of everyday life. Rather than emphasizing external performance metrics alone, XB invites participants to evaluate practices through felt experience, including whether a practice helps them feel better, worse, or the same. Although prior XB studies have shown promise for supporting health behavior change, less is known about the experiential and interpretive processes through which participants use XB to connect felt experience with action, adaptation, and continued practice. Objective: This study aimed to develop a preliminary prototheory of tuning to explain how participants used felt experience to guide eating and movement experimentation within XB. We define tuning as a dynamic, person-centered process through which individuals learn to sense, interpret, and act on bodily and contextual feedback during guided experimentation. Methods: We conducted a secondary, post hoc qualitative inquiry using interpretive description, reflexive thematic analysis, and abductive analysis. The qualitative corpus consisted of responses to 39 open-text postintervention survey questions completed across 3 survey sections. Descriptive implementation information was used to characterize participant flow and survey completion. A total of 44 participants enrolled and accessed the XB app. Of these, 12 completed the general postintervention survey, 11 completed the MOVE survey section, and 8 completed the XB app and implementation section. Self-determination theory and activity theory were used as sensitizing frameworks rather than fixed coding templates. Analysis involved iterative coding, analytic memoing, conceptual mapping, and team-based review to develop a preliminary prototheory of tuning. Results: The analysis resulted in a prototheory of tuning organized around recursive loops linking action, felt experience, interpretation, adaptation, and future action. Participants described XB as creating a low-pressure structure for trying practices, noticing bodily and experiential signals, interpreting those signals through practical health heuristics, and adapting practices to their bodies, routines, social relationships, and environments. Over time, repeated experimentation appeared to support the development of portable knowledge, skills, and practices, including movement snacks, eating heuristics, and an ongoing experimental orientation toward health behavior. Social, material, and environmental conditions shaped whether and how participants could engage in tuning, particularly across home, work, and family contexts. Conclusions: Tuning offers a preliminary conceptual lens for understanding how guided experimentation may support health behavior change by helping participants connect action, felt experience, interpretation, and adaptation. Rather than positioning behavior change as compliance with external prescriptions or metrics, the tuning prototheory foregrounds how individuals may cultivate the capacity to notice, interpret, and act on felt experience in context. Future prospective qualitative and mixed methods studies should test, refine, and potentially challenge this prototheory across more diverse populations and implementation settings.

Indexed as

HeuristicsLearningAdultFemaleHealth BehaviorHumansMaleQualitative ResearchSurveys and Questionnairesbehavioral changedietary habitsdigital healthexercisemHealthmovementqualitative research

Identifiers

PMID42766636
PMCPMC13592457

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.