ArticleJournal of natural medicines2026
Bioactivity-guided optimization of Gastrodia elata cultivation: integrated modulation of spawn wood length, tree species and pit size.
Article in Journal of natural medicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Gastrodia elata serves as a natural product source for treating neuroinflammation and neurodegenerative diseases, yet inconsistent planting practices cause significant variations in its therapeutic components. This study investigated how spawn wood length, tree species and pit size influenced yield and bioactive compound accumulation. Bioactive compounds were quantified by HPLC, and anti-neuroinflammatory activities of major components were validated in LPS-induced BV2 microglial cells. The highest total and graded yields were achieved with 15 cm spawn wood length. Birch and cherry species yielded significantly higher production, with birch showing the highest accumulation of parishin A and B. The 0.4 m
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